Evidence map›Paper›PMID 29096045›Full record

ArticleChemistry (Weinheim an der Bergstrasse, Germany)2018

Water-Soluble Nanoparticle Receptors Supramolecularly Coded for Acidic Peptides.

Shixin Fa, Yan Zhao

Open access · greenAbstract read
In one paragraph

Article in Chemistry (Weinheim an der Bergstrasse, Germany), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Substrate Protection in Controlled Enzymatic Transformation of Peptides and Proteins.Chembiochem : a European journal of chemical biology · 2021
    Article
  6. Sequence-Selective Protection of Peptides from Proteolysis.Angewandte Chemie (International ed. in English) · 2021
    Article
  7. Article
  8. Article
  9. Article
  10. Dandelion flower-like micelles.Chemical science · 2019
    Article
  11. Article
  12. General Method for Peptide Recognition in Water through Bioinspired Complementarity.Chemistry of materials : a publication of the American Chemical Society · 2019
    Article
  13. Article
  14. Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Shixin FaDepartment of Chemistry, Iowa State University, Ames, IA, 50011-3111, USA.ORCID http://orcid.org/0000-0003-2261-409X
Yan ZhaoDepartment of Chemistry, Iowa State University, Ames, IA, 50011-3111, USA.ORCID http://orcid.org/0000-0003-1215-2565
Iowa State University · US

Funding

Biomimetic Receptors for Small Hydrophobic Drugs, Carbohydrates, and OligopeptidesR01GM113883 · NIGMS · IOWA STATE UNIVERSITY · PI ZHAO, YAN · 2015 to 2018
$1.1M
NIGMS NIH HHS R01 GM113883
6 · The paper itself

Abstract

Sequence-specific recognition of peptides is of enormous importance to many chemical and biological applications, but has been difficult to achieve due to the minute differences in the side chains of amino acids. Acidic peptides are known to play important roles in cell growth and gene expression. In this work, we report molecularly imprinted micelles coded with molecular recognition information for the acidic and hydrophobic side chains of acidic peptides. The imprinted receptors could distinguish acidic amino acids from other polar and nonpolar amino acids, with dissociation constants of tens of nanomolar for biologically active peptides containing up to 18 amino acids.

Indexed as

Amino AcidsAmino Acids, BasicHydrophobic and Hydrophilic InteractionsNanoparticlesPeptidesWaterAmino AcidsAmino Acids, BasicPeptidesWateramino acidsmicellesmolecular recognitionnanoparticlespeptides

Identifiers

PMID29096045
PMCPMC5891325
OpenAlexW2766608469

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.