Evidence map›Paper›PMID 29095899›Full record

SynthesisPloS one2017

A systematic review of emergency department based HIV testing and linkage to care initiatives in low resource settings.

Bhakti Hansoti, Gabor D Kelen, Thomas C Quinn, Madeleine M Whalen, Taylor T DesRosiers, Steven J Reynolds, Andrew Redd, Richard E Rothman

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 3 pooled it
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 3 syntheses or guidelines pooled it, 32 citations in OpenAlex.

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  13. Factors associated with HIV testing among patients seeking emergent injury care in Kigali, Rwanda.African journal of emergency medicine : Revue africaine de la medecine d'urgence · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Bhakti HansotiDepartment of Emergency Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America.ORCID http://orcid.org/0000-0003-0188-9764
Gabor D KelenDepartment of Emergency Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America.
Thomas C QuinnDivision of Intramural Research, NIAID/NIH, Baltimore, Maryland, United States of America.
Madeleine M WhalenDepartment of Emergency Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America.
Taylor T DesRosiersDepartment of Emergency Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America.
Steven J ReynoldsDivision of Intramural Research, NIAID/NIH, Baltimore, Maryland, United States of America.
Andrew ReddDivision of Intramural Research, NIAID/NIH, Baltimore, Maryland, United States of America.
Richard E RothmanDepartment of Emergency Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America.
Johns Hopkins University · USNational Institute on Drug Abuse · US

Funding

Vaccine Response and Immunotherapeutics SWGP30AI094189 · NIAID · JOHNS HOPKINS UNIVERSITY · PI Richard E. Chaisson · 2012 to 2026
$67.0M
International Studies of the Acquired Immune Deficiency Syndrome (AIDS)ZIAAI000361 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI REDD, ANDREW · 2009 to 2025
$15.8M
NIAID NIH HHS P30 AI094189
6 · The paper itself

Abstract

introductionOnly 45% of people currently living with HIV infection in sub-Saharan Africa are aware of their HIV status. Unmet testing needs may be addressed by utilizing the Emergency Department (ED) as an innovative testing venue in low and middle-income countries (LMICs). The purpose of this review is to examine the burden of HIV infection described in EDs in LMICs, with a focus on summarizing the implementation of various ED-based HIV testing strategies. METHODOLOGY AND

resultsWe performed a systematic review of Pubmed, Embase, Scopus, Web of Science and the Cochrane Library on June 12, 2016. A three-concept search was employed with emergency medicine (e.g., Emergency department, emergency medical services), HIV/AIDS (e.g., human immunodeficiency virus, acquired immunodeficiency syndrome), and LMIC terms (e.g., developing country, under developed countries, specific country names). The search returned 2026 unique articles. Of these, thirteen met inclusion criteria and were included in the final review. There was a large variation in the reported prevalence of HIV infection in the ED population ranging from to 2.14% in India to 43.3% in Uganda. The proportion HIV positive patients with previously undiagnosed infection ranged from 90% to 65.22%.

conclusionIn the United States ED-based HIV testing strategies have been front and center at curbing the HIV epidemic. The limited number of ED-based studies we observed in this study may represent the paucity of HIV testing in this venue in LMICs. All of the studies in this review demonstrated a high prevalence of HIV infection in the ED and an extraordinarily high percentage of previously undiagnosed HIV infection. Although the numbers of published reports are few, these diverse studies imply that in HIV endemic low resource settings EDs carry a large burden of undiagnosed HIV infections and may offer a unique testing venue.

Indexed as

Health Care RationingAIDS SerodiagnosisEmergency Service, HospitalFemaleHIV InfectionsHIV SeroprevalenceHumansIndiaMaleUganda

Identifiers

PMID29095899
PMCPMC5667894
OpenAlexW2767030821

What OpenQuestion holds

Textmetadata
LicenceCC0
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.