Evidence map›Paper›PMID 29095375›Full record

ArticleNursing research

Negative Temperature Differential in Preterm Infants Less Than 29 Weeks Gestational Age: Associations With Infection and Maternal Smoking.

Robin B Knobel-Dail, Richard Sloane, Diane Holditch-Davis, David T Tanaka

Abstract read
In one paragraph

Article in Nursing research. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Neonatal autonomic regulation as a predictor of autism symptoms in very preterm infants.Journal of perinatology : official journal of the California Perinatal Association · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Robin B Knobel-DailRobin B. Knobel-Dail, PhD, RN, FAAN, is Professor and Associate Dean for Faculty Affairs, College of Nursing, University of South Carolina, Columbia. At the time this research was completed, she was Associate Professor, Duke University School of Nursing and Duke University School of Medicine, Durham, North Carolina. Richard Sloane, MPH, is Biostatistician and Senior Staff, Duke University Center for the Study of Aging and Human Development, Durham, North Carolina. Diane Holditch-Davis, PhD, RN, FAAN, is Professor Emeritus, Duke University School of Nursing, Durham, North Carolina. David T. Tanaka, MD, is Professor, Department of Pediatrics and Neonatology, Duke University School of Medicine, Durham, North Carolina.
Richard Sloane
Diane Holditch-Davis
David T Tanaka

Funding

Temperature & Vasomotor Tone During the First 5 Days in Preterms Less than 1000gR15NR012157 · NINR · DUKE UNIVERSITY · PI DAIL, ROBIN BRITT · 2010 to 2010
$479k
NINR NIH HHS R15 NR012157
6 · The paper itself

Abstract

backgroundHypothermia is related to increased morbidity and mortality in very preterm infants; continuous temperature monitoring is necessary. Thermoregulation is limited in preterm infants.

objectivesThe purpose of the research was to assess and describe negative temperature differential (NTD) and assess the associations of NTD with infant demographic characteristics, medical history, and clinical events.

methodsAn exploratory, case study design was used. Abdominal and foot temperature was measured every minute over the first 2 weeks of life in 22 preterm infants at less than 29 weeks gestational age.

resultsAll infants experienced NTD. Daily NTD in all infants across all study days ranged from 0 to 70.7%; 2-week mean NTD over all infants ranged from 7.3% to 38.5%. Four infants treated for late onset of infection had a higher NTD than 18 infants without infection (M = 27.8%, SD = 9.52 vs. M = 16.4%, SD = 5.34, p < .05). Although not statistically significant, higher mean percentage of NTD was noted in infants having early onset infection (24.1% vs. 16.4%), African American race (20.0% vs. 15.3%), and/or being born to a mother who smoked during pregnancy (26.6% vs. 16.7%). DISCUSSION: A larger study is needed to examine associations between NTD and race, maternal smoking history, and infection. NTD might be used as a biomarker to guide acute clinical care and identify infants at risk for acute and chronic morbidity.

Indexed as

Infant, PrematureBody TemperatureFemaleGestational AgeHumansHypothermiaInfant, NewbornInfant, Premature, DiseasesIntensive Care Units, NeonatalMalePregnancyPrenatal Exposure Delayed EffectsPrognosisSmoking

Identifiers

PMID29095375
PMCPMC5679714

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.