Evidence map›Paper›PMID 29094789›Full record

ArticleNeurogastroenterology and motility2018

Relationship between symptoms and quality of life in fecal incontinence.

K Bedard, S Heymen, O S Palsson, A E Bharucha, W E Whitehead

Open access · greenAbstract read
In one paragraph

Article in Neurogastroenterology and motility, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 2 pooled it
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 2 syntheses or guidelines pooled it, 34 citations in OpenAlex.

  1. Global Prevalence of Fecal Incontinence in Community-Dwelling Adults: A Systematic Review and Meta-analysis.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2024
    Pooled it
  2. Pooled it
  3. Trial
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Faecal incontinence in adults.Nature reviews. Disease primers · 2022
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

K BedardSchool of Medicine, New York Medical College, Valhalla, NY, USA.
S HeymenDivision of Gastroenterology and Hepatology, University of North Carolina Chapel Hill, Chapel Hill, NC, USA.
O S PalssonDivision of Gastroenterology and Hepatology, Center for Functional GI and Motility Disorders, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
A E BharuchaDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Mayo Clinic, Rochester, MN, USA.ORCID 0000-0002-7644-0390
W E WhiteheadDivision of Gastroenterology and Hepatology, Center for Functional GI and Motility Disorders, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.ORCID 0000-0001-6587-7602
University of North Carolina at Chapel Hill · USMayo Clinic in Arizona · USNew York Medical College · US

Funding

Pathophysiology of Anorectal DisordersR01DK078924 · NIDDK · MAYO CLINIC ROCHESTER · PI BHARUCHA, ADIL E. · 2008 to 2023
$5.0M
UNC-CH Summer Research Training in Aging for Medical StudentsT35AG038047 · NIA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI JAN BUSBY-WHITEHEAD · 2010 to 2026
$1.4M
Comparative Effectiveness of Biofeedback, Sacral Nerve Stimulation, and Injectable Bulking Agents for Treatment of Fecal IncontinenceU34DK109191 · NIDDK · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BHARUCHA, ADIL E., GANTZ, MARIE G · 2016 to 2017
$711k
NIA NIH HHS T35 AG038047NIDDK NIH HHS R01 DK078924NIDDK NIH HHS U34 DK109191
6 · The paper itself

Abstract

backgroundMost measures of fecal incontinence (FI) severity assess the frequency of solid and liquid FI, but may incorporate other features. We compared two scales-the Fecal Incontinence Severity Score (FISS) and Fecal Incontinence Severity Index (FISI)-to determine which questionnaire and which individual questions predict FI Quality of Life (FIQOL).

methodsA national sample of American adults completed a health questionnaire, and 234 with monthly FI were selected. Participants completed assessments of FI severity, FIQOL, and somatization. Stepwise linear regression models evaluated whether FISS and FISI total scores, or individual items on the FISS and FISI predicted FIQOL after adjusting for gender, age, income, and somatization (Brief Symptom Inventory-18). KEY

resultsReliable responses were provided by 186. Age was 49 years, and 52% were women. The mean FISS score was 8.4 (95% confidence interval [CI] 8.0-8.9, 13 questions) and mean FISI was 29.9 (95% CI 27.4-32.4, 62 questions), indicating moderate FI severity. The mean FIQOL was 2.6 (95% CI 2.4-2.7, 5 questions). Lower income, greater somatization, and total FISS and FISI scores explained 69% of FIQOL; and total FISS and FISI scores were independent predictors. On the FISS, frequency, amount, and urgency to defecate were independently associated with FIQOL. After adding somatization, all but amount remained significant. For the FISI scale, solid and liquid FI and gas were significant predictors, but adjusting for somatization excluded solid FI. CONCLUSIONS AND INFERENCES: Five variables independently explained FIQOL: overall frequency of FI, frequency of liquid and gas leakage, urgency, and somatization.

Indexed as

AdultAgedAged, 80 and overCohort StudiesFecal IncontinenceFemaleHumansMaleMiddle AgedQuality of LifeSeverity of Illness IndexSurveys and QuestionnairesYoung Adultfecal incontinencequality of lifesomatization/comorbidity

Identifiers

PMID29094789
PMCPMC5869683
OpenAlexW2765440628

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.