Evidence map›Paper›PMID 29094456›Full record

Observational studyBJOG : an international journal of obstetrics and gynaecology2018

A prospective cause of death classification system for maternal deaths in low and middle-income countries: results from the Global Network Maternal Newborn Health Registry.

O Pasha, E M McClure, S Saleem, S S Tikmani, A Lokangaka, A Tshefu, C L Bose, M Bauserman, M Mwenechanya, E Chomba and 19 more

Abstract readObservational Study
In one paragraph

Observational study in BJOG : an international journal of obstetrics and gynaecology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Article
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  4. Postpartum hemorrhage in electronic health records: risk factors at admission and in-hospital occurrence.Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2024
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

29 authors.

O PashaAga Khan University, Karachi, Pakistan.
E M McClureRTI International, Durham, NC, USA.
S SaleemAga Khan University, Karachi, Pakistan.
S S TikmaniAga Khan University, Karachi, Pakistan.
A LokangakaKinshasa School of Public Health, Kinshasa, Democratic Republic of the Congo.
A TshefuKinshasa School of Public Health, Kinshasa, Democratic Republic of the Congo.
C L BoseUniversity of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
M BausermanUniversity of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
M MwenechanyaUniversity Teaching Hospital, Lusaka, Zambia.
E ChombaUniversity Teaching Hospital, Lusaka, Zambia.
W A CarloUniversity of Alabama at Birmingham, Birmingham, AL, USA.
A L GarcesINCAP, Guatemala City, Guatemala.
L FigueroaINCAP, Guatemala City, Guatemala.
K M HambidgeUniversity of Colorado, School of Medicine, Denver, CO, USA.
N F KrebsUniversity of Colorado, School of Medicine, Denver, CO, USA.
S GoudarKLE University's JN Medical College, Belagavi, India.
B S KodkanyKLE University's JN Medical College, Belagavi, India.
S DhadedKLE University's JN Medical College, Belagavi, India.
R J DermanThomas Jefferson University, Philadelphia, PA, USA.
A PatelLata Medical Research Foundation, Nagpur, India.
P L HibberdBoston University, Boston, MA, USA.
F EsamaiMoi University, Eldoret, Kenya.
C TengeMoi University, Eldoret, Kenya.
E A LiechtyIndiana University, Indianapolis, IN, USA.
J L MooreRTI International, Durham, NC, USA.
D D WallaceRTI International, Durham, NC, USA.
M Koso-ThomasNICHD, Rockville, MD, USA.
M MiodovnikNICHD, Rockville, MD, USA.
R L GoldenbergColumbia University School of Medicine, New York, NY, USA.

Funding

Zika in Pregnancy Supplemental Funding requestU01HD040636 · NICHD · RESEARCH TRIANGLE INSTITUTE · PI MCCLURE, ELIZABETH M · 2001 to 2017
$37.5M
Global Network for Women's and Children's Health Research Data Coordinating CenterU24HD092094 · NICHD · RESEARCH TRIANGLE INSTITUTE · PI Elizabeth M McClure · 2017 to 2026
$17.8M
UAB/AKU Global Network Research UnitU01HD040607 · NICHD · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI GOLDENBERG, ROBERT L · 2001 to 2012
$8.5M
Complementary feeding: a Global Network cluster randomized controlled trialU01HD040657 · NICHD · UNIVERSITY OF COLORADO DENVER · PI HAMBIDGE, K MICHAEL · 2001 to 2012
$8.1M
UMKC-JNMC Global Network for Women's and Children's Health Research UnitU01HD042372 · NICHD · UNIVERSITY OF MISSOURI KANSAS CITY · PI DERMAN, RICHARD J · 2001 to 2012
$6.9M
Neonatal Resuscitation in Developing CountriesU01HD043464 · NICHD · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI CARLO FONT, WALDEMAR A. · 2003 to 2012
$6.6M
Evidence-Based Global Health Interventions for Mothers and Children, ArgentinaU01HD040477 · NICHD · UNIVERSITY OF NORTH CAROLINA CHAPEL HILL · PI BUEKENS, PIERRE · 2001 to 2013
$5.6M
Boston University/Lata Medical Research Foundation Global Network for Women's Children's Health Research UnitUG1HD078439 · NICHD · BOSTON UNIVERSITY MEDICAL CAMPUS · PI Patricia L Hibberd · 2018 to 2026
$5.5M
TJU-JNMC Global Network for Women's & Children's Health Research UnitUG1HD076457 · NICHD · THOMAS JEFFERSON UNIVERSITY · PI RICHARD J DERMAN · 2018 to 2026
$5.5M
Nutrition-specific interventions to improve long-term maternal-child health outcomesUG1HD076474 · NICHD · UNIVERSITY OF COLORADO DENVER · PI Edwin Jose Asturias, NANCY F KREBS · 2018 to 2026
$5.4M
The Global Network and Preconception Maternal NutritionU10HD076474 · NICHD · UNIVERSITY OF COLORADO DENVER · PI KREBS, NANCY F · 2013 to 2017
$5.1M
Improving Quality of Care for the Treatment of Childhood PneumoniaU01HD058322 · NICHD · TUFTS UNIVERSITY BOSTON · PI HIBBERD, PATRICIA L · 2008 to 2012
$4.0M
NCCIH NIH HHS K24 AT003683NICHD NIH HHS U01 HD040477NICHD NIH HHS U01 HD040607NICHD NIH HHS U01 HD040636NICHD NIH HHS U01 HD040657NICHD NIH HHS U01 HD042372NICHD NIH HHS U01 HD043464NICHD NIH HHS U01 HD058322NICHD NIH HHS U01 HD058326NICHD NIH HHS U10 HD076457NICHD NIH HHS U10 HD076465NICHD NIH HHS U10 HD076474NICHD NIH HHS U10 HD078438NICHD NIH HHS U10 HD078439NICHD NIH HHS U24 HD092094NICHD NIH HHS UG1 HD076457NICHD NIH HHS UG1 HD076461NICHD NIH HHS UG1 HD076474NICHD NIH HHS UG1 HD078439
6 · The paper itself

Abstract

objectiveTo describe the causes of maternal death in a population-based cohort in six low- and middle-income countries using a standardised, hierarchical, algorithmic cause of death (COD) methodology.

designA population-based, prospective observational study.

settingSeven sites in six low- to middle-income countries including the Democratic Republic of the Congo (DRC), Guatemala, India (two sites), Kenya, Pakistan and Zambia. POPULATION: All deaths among pregnant women resident in the study sites from 2014 to December 2016.

methodsFor women who died, we used a standardised questionnaire to collect clinical data regarding maternal conditions present during pregnancy and delivery. These data were analysed using a computer-based algorithm to assign cause of maternal death based on the International Classification of Disease-Maternal Mortality system (trauma, termination of pregnancy-related, eclampsia, haemorrhage, pregnancy-related infection and medical conditions). We also compared the COD results to healthcare-provider-assigned maternal COD.

main outcome measuresAssigned causes of maternal mortality.

resultsAmong 158 205 women, there were 221 maternal deaths. The most common algorithm-assigned maternal COD were obstetric haemorrhage (38.6%), pregnancy-related infection (26.4%) and pre-eclampsia/eclampsia (18.2%). Agreement between algorithm-assigned COD and COD assigned by healthcare providers ranged from 75% for haemorrhage to 25% for medical causes coincident to pregnancy.

conclusionsThe major maternal COD in the Global Network sites were haemorrhage, pregnancy-related infection and pre-eclampsia/eclampsia. This system could allow public health programmes in low- and middle-income countries to generate transparent and comparable data for maternal COD across time or regions. TWEETABLE ABSTRACT: An algorithmic system for determining maternal cause of death in low-resource settings is described.

Indexed as

Cause of DeathBlack PeopleDemocratic Republic of the CongoDeveloping CountriesFemaleGlobal HealthGuatemalaHumansIncomeIndiaKenyaMaternal DeathMaternal MortalityPakistanPregnancyPregnancy ComplicationsCause of deathclassificationlow- and middle-income countriesmaternal mortality

Identifiers

PMID29094456
PMCPMC6298604

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.