Evidence map›Paper›PMID 29094416›Full record

ArticleThe European journal of neuroscience2017

MAP6 interacts with Tctex1 and Ca

Jacques Brocard, Fabrice Dufour, Sylvie Gory-Fauré, Christophe Arnoult, Christophe Bosc, Eric Denarier, Leticia Peris, Yasmina Saoudi, Michel De Waard, Annie Andrieux

Open access · hybridAbstract read
In one paragraph

Article in The European journal of neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.5field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Proper localization of the SCA13-linked KNeurobiology of disease · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Modulation of voltage-gated CaChannels (Austin, Tex.) · 2020
    Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Jacques BrocardU1216, INSERM, Grenoble, F-38000, France.
Fabrice DufourU1216, INSERM, Grenoble, F-38000, France.
Sylvie Gory-FauréU1216, INSERM, Grenoble, F-38000, France.
Christophe ArnoultU1209, INSERM, Grenoble, France.
Christophe BoscU1216, INSERM, Grenoble, F-38000, France.
Eric DenarierU1216, INSERM, Grenoble, F-38000, France.
Leticia PerisU1216, INSERM, Grenoble, F-38000, France.
Yasmina SaoudiU1216, INSERM, Grenoble, F-38000, France.
Michel De WaardU1087, INSERM, Nantes, France.
Annie AndrieuxU1216, INSERM, Grenoble, F-38000, France.ORCID http://orcid.org/0000-0002-4022-6405
Inserm · FRCentre National de la Recherche Scientifique · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

MAP6 proteins were first described as microtubule-stabilizing agents, whose properties were thought to be essential for neuronal development and maintenance of complex neuronal networks. However, deletion of all MAP6 isoforms in MAP6 KO mice does not lead to dramatic morphological aberrations of the brain but rather to alterations in multiple neurotransmissions and severe behavioural impairments. A search for protein partners of MAP6 proteins identified Tctex1 - a dynein light chain with multiple non-microtubule-related functions. The involvement of Tctex1 in calcium signalling led to investigate it in MAP6 KO neurons. In this study, we show that functional Ca

Indexed as

AnimalsBinding SitesCalcium Channels, N-TypeCalcium SignalingCells, CulturedDyneinsFemaleHippocampusMiceMice, KnockoutMicrotubule-Associated ProteinsNeuronsProtein BindingCacna1b protein, mouseCalcium Channels, N-TypeDyneinsDynlt1b protein, mouseMicrotubule-Associated ProteinsMtap6 protein, mousehippocampal neuronsin vitro interactionsmicrotubulesplasma membranevesiclesyeast two-hybrid

Identifiers

PMID29094416
PMCPMC5765474
OpenAlexW2765660376

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.