ArticleJAMA psychiatry2017
Inference in Psychiatry via 2-Sample Mendelian Randomization-From Association to Causal Pathway?
Article in JAMA psychiatry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Mendelian randomization study of gastroesophageal reflux disease and major depression.PloS one · 2023Pooled it
- Gene-environment correlations and causal effects of childhood maltreatment on physical and mental health: a genetically informed approach.The lancet. Psychiatry · 2021Pooled it
- Assessment of Bidirectional Relationships Between Physical Activity and Depression Among Adults: A 2-Sample Mendelian Randomization Study.JAMA psychiatry · 2019Pooled it
- Are There Causal Associations Between Obsessive-Compulsive Disorder and Cardiometabolic Phenotypes? A Genetic Correlation and Bi-Directional Mendelian Randomization Study.American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics · 2026Article
- Systemic Inflammatory Factors and Neuropsychiatric Disorders: A Bidirectional Mendelian Randomization Study.Brain and behavior · 2025Article
- Causal relationship between major depressive disorder, anxiety disorder and constipation: a two-sample Mendelian randomization study.BMC gastroenterology · 2024Article
- Identification of novel protein biomarkers and therapeutic targets for ankylosing spondylitis using human circulating plasma proteomics and genome analysis.Analytical and bioanalytical chemistry · 2024Article
- Mediating pathways between attention deficit hyperactivity disorder and type 2 diabetes mellitus: evidence from a two-step and multivariable Mendelian randomization study.Epidemiology and psychiatric sciences · 2024Article
- Causal Relationships between Lymphocyte Subsets and Risk of Coronary Artery Disease: A Two-Sample Mendelian Randomization Study.Reviews in cardiovascular medicine · 2024Article
- Predicting psychiatric risk: IgG N-glycosylation traits as biomarkers for mental health.Frontiers in psychiatry · 2024Article
- Associations of Schizophrenia and Major Depressive Disorder with Constipation: A Mendelian Randomization Study.Clinical and experimental gastroenterology · 2024Article
- The potential causal relationship between various lifestyles and depression: a univariable and multivariable Mendelian randomization study.Frontiers in psychiatry · 2024Article
- Causal effect analysis of estrogen receptor associated breast cancer and clear cell ovarian cancer.American journal of translational research · 2024Article
- Genetic insights into the causal relationship between physical activity and cognitive functioning.Scientific reports · 2023Article
- Ankylosing spondylitis and psychiatric disorders in European population: a Mendelian randomization study.Frontiers in immunology · 2023Article
- Modifiable risk factors of major depressive disorder: A Mendelian randomization study.PloS one · 2023Article
- An Exposure-Wide and Mendelian Randomization Approach to Identifying Modifiable Factors for the Prevention of Depression.The American journal of psychiatry · 2020Article
- Physical activity, exercise, and mental disorders: it is time to move on.Trends in psychiatry and psychotherapyReview
- Causal effects of physical activity on the risk of overall ovarian cancer: A Mendelian randomization study.Digital healthArticle
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
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Identifiers
29094155What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.