Evidence map›Paper›PMID 29094093›Full record

ArticleJournal of global oncology2017

Use of Palliative Cisplatinum for Advanced Cervical Cancer in a Resource-Poor Setting: A Case Series From Kenya.

Elkanah Orang'o, Peter Itsura, Philip Tonui, Hellen Muliro, Barry Rosen, Luc van Lonkhuijzen

Open access · goldAbstract read
In one paragraph

Article in Journal of global oncology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Elkanah Orang'o, , , and , Moi University School of Medicine, Eldoret, Kenya; , Oakland University, Rochester, MI; , Academic Medical Center, Amsterdam, the Netherlands.
Peter Itsura, , , and , Moi University School of Medicine, Eldoret, Kenya; , Oakland University, Rochester, MI; , Academic Medical Center, Amsterdam, the Netherlands.
Philip Tonui, , , and , Moi University School of Medicine, Eldoret, Kenya; , Oakland University, Rochester, MI; , Academic Medical Center, Amsterdam, the Netherlands.
Hellen Muliro, , , and , Moi University School of Medicine, Eldoret, Kenya; , Oakland University, Rochester, MI; , Academic Medical Center, Amsterdam, the Netherlands.
Barry Rosen, , , and , Moi University School of Medicine, Eldoret, Kenya; , Oakland University, Rochester, MI; , Academic Medical Center, Amsterdam, the Netherlands.
Luc van Lonkhuijzen, , , and , Moi University School of Medicine, Eldoret, Kenya; , Oakland University, Rochester, MI; , Academic Medical Center, Amsterdam, the Netherlands.
Moi University · KE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate the effectiveness and feasibility of cisplatinum for palliative treatment of advanced cervical cancer in a resource-poor setting.

methodsAn observational case series is reported from a university teaching hospital in Kenya. All women presenting with advanced cervical cancer and planned for palliative cisplatinum therapy from 2010 to 2014 were included. Women were treated with cisplatinum 50 mg/m

resultsOf the women who originally presented with bleeding, 62% reported improvement in this symptom, 31.3% reported the bleeding completely stopped, 58% had improvement of their vaginal discharge, and 20.5% reported complete resolution. Of the women who presented with pain, 54% reported improvement; 30.9% reported pain had completely resolved. After each treatment cycle, approximately 30% of patients did not return for their next treatment.

conclusionCisplatinum as palliative treatment of advanced cervical cancer is feasible in a resource-poor setting and leads to effective symptom control. However, unknown barriers may inhibit women from returning for regular treatment.

Identifiers

PMID29094093
PMCPMC5646886
OpenAlexW2547048698

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.