Evidence map›Paper›PMID 29094084›Full record

ArticleJournal of global oncology2017

Outcomes in Lung Cancer: 9-Year Experience From a Tertiary Cancer Center in India.

Aditya Navile Murali, Venkatraman Radhakrishnan, Trivadi S Ganesan, Rejiv Rajendranath, Prasanth Ganesan, Ganesarajah Selvaluxmy, Rajaraman Swaminathan, Shirley Sundersingh, Arvind Krishnamurthy, Tenali Gnana Sagar

Abstract read
In one paragraph

Article in Journal of global oncology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Article
  2. Article
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  5. Uniqueness of lung cancer in Southeast Asia.The Lancet regional health. Southeast Asia · 2024
    Review
  6. Surgery for lung cancer: insight from a state cancer centre in India.Indian journal of thoracic and cardiovascular surgery · 2024
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Navigating patient journey in early diagnosis of lung cancer in India.Lung India : official organ of Indian Chest Society
    Review
  17. Article
  18. Survival Rates and Predictors of Mortality in Lung Cancer: A Multi-Centre Study in Kerala.Indian journal of community medicine : official publication of Indian Association of Preventive & Social Medicine
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Aditya Navile MuraliAll authors: Cancer Institute (WIA), Adyar, Chennai, India.
Venkatraman RadhakrishnanAll authors: Cancer Institute (WIA), Adyar, Chennai, India.
Trivadi S GanesanAll authors: Cancer Institute (WIA), Adyar, Chennai, India.
Rejiv RajendranathAll authors: Cancer Institute (WIA), Adyar, Chennai, India.
Prasanth GanesanAll authors: Cancer Institute (WIA), Adyar, Chennai, India.
Ganesarajah SelvaluxmyAll authors: Cancer Institute (WIA), Adyar, Chennai, India.
Rajaraman SwaminathanAll authors: Cancer Institute (WIA), Adyar, Chennai, India.
Shirley SundersinghAll authors: Cancer Institute (WIA), Adyar, Chennai, India.
Arvind KrishnamurthyAll authors: Cancer Institute (WIA), Adyar, Chennai, India.
Tenali Gnana SagarAll authors: Cancer Institute (WIA), Adyar, Chennai, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeLung cancer is the most common cause of cancer mortality in the world. There are limited studies on survival outcomes of lung cancer in developing countries such as India. This study analyzed the outcomes of patients with lung cancer who underwent treatment at Cancer Institute (WIA), Chennai, India, between 2006 and 2015 to determine survival outcomes and identify prognostic factors. PATIENTS AND

methodsIn all, 678 patients with lung cancer underwent treatment. Median age was 58 years, and 91% of patients had non-small-cell lung cancer (NSCLC). Testing for epidermal growth factor receptor mutation was performed in 132 of 347 patients and 61 (46%) were positive.

resultsMedian progression-free survival was 6.9 months and overall survival (OS) was 7.6 months for patients with NSCLC. Median progression-free survival was 6 months and OS was 7.2 months for patients with small-cell lung cancer. On multivariable analysis, the factors found to be significantly associated with inferior OS in NSCLC included nonadenocarcinoma histology, performance status more than 2, and stage. In small-cell lung cancer, younger age and earlier stage at presentation showed significantly better survival.

conclusionOur study highlights the challenges faced in treating lung cancer in India. Although median survival in advanced-stage lung cancer is still poor, strategies such as personalized medicine and use of second-line and maintenance chemotherapy may significantly improve the survival in patients with advanced-stage lung cancer in developing countries.

Identifiers

PMID29094084
PMCPMC5646892

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.