Evidence map›Paper›PMID 29094060›Full record

ArticleBio-protocol2017

Representation-mediated Aversion as a Model to Study Psychotic-like States in Mice.

Arnau Busquets-Garcia, Edgar Soria-Gómez, Guillaume Ferreira, Giovanni Marsicano

Open access · greenAbstract read
In one paragraph

Article in Bio-protocol, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Hallucinations and Strong Priors.Trends in cognitive sciences · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Arnau Busquets-GarciaINSERM, U1215 NeuroCentre Magendie, Bordeaux, France.
Edgar Soria-GómezINSERM, U1215 NeuroCentre Magendie, Bordeaux, France.
Guillaume FerreiraUniversity of Bordeaux, Bordeaux, France.
Giovanni MarsicanoINSERM, U1215 NeuroCentre Magendie, Bordeaux, France.
Université de Bordeaux · FRInserm · FRInstitut National de Recherche en Santé Publique · ML

Funding

European Research Council 260515
6 · The paper itself

Abstract

Several paradigms for rodent models of the cognitive and negative endophenotypes found in schizophrenic patients have been proposed. However, significant efforts are needed in order to study the pathophysiology of schizophrenia-related positive symptoms. Recently, it has been shown that these positive symptoms can be studied in rats by using representation-mediated learning. This learning measure the accuracy of mental representations of reality, also called 'reality testing'. Alterations in 'reality testing' performance can be an indication of an impairment in perception which is a clear hallmark of positive psychotic-like states. Thus, we describe here a mouse task adapted from previous findings based on a sensory preconditioning task. With this task, associations made between different neutral stimuli (

Indexed as

DelusionsPositive symptomsReality testingRepresentation-mediated learningSchizophrenia

Identifiers

PMID29094060
PMCPMC5662143
OpenAlexW2706089593

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.