Evidence map›Paper›PMID 29094025›Full record

ArticleFrontiers in cellular and infection microbiology2017

Corilagin Counteracts IL-13Rα1 Signaling Pathway in Macrophages to Mitigate Schistosome Egg-Induced Hepatic Fibrosis.

Yi-Qing Li, Yun-Fei Chen, Yi-Ping Dang, Yao Wang, Zhen-Zhong Shang, Qian Ma, Yu-Jie Wang, Juan Zhang, Lei Luo, Quan-Qiang Li and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.8field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 35 citations in OpenAlex.

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  17. Corilagin Alleviates Ang II-Induced Cardiac Fibrosis by Regulating the PTEN/AKT/mTOR Pathway.Dose-response : a publication of International Hormesis Society
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 1 country.

Yi-Qing LiDepartment of Vascular Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Yun-Fei ChenDepartment of Vascular Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Yi-Ping DangDepartment of Vascular Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Yao WangSchool of Clinical Medicine, Hubei University of Chinese Medicine, Wuhan, China.
Zhen-Zhong ShangSchool of Basic Medical Sciences, Guangxi University of Chinese Medicine, Nanning, China.
Qian MaSchool of Life Science, Hubei University, Wuhan, China.
Yu-Jie WangDepartment of Vascular Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Juan ZhangSchool of Clinical Medicine, Hubei University of Chinese Medicine, Wuhan, China.
Lei LuoSchool of Clinical Medicine, Hubei University of Chinese Medicine, Wuhan, China.
Quan-Qiang LiSchool of Clinical Medicine, Guangxi University of Chinese Medicine, Nanning, China.
Lei ZhaoDepartment of Infectious Diseases, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Hubei University of Chinese Medicine · CNUnion Hospital · CNGuangxi University of Chinese Medicine · CNHuazhong University of Science and Technology · CNHubei University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The IL-13Rα1 signaling pathway and M2 macrophages play crucial roles in schistosome egg-induced hepatic fibrosis via the expression of pro-fibrotic molecules. This study aims to investigate the inhibitory effect and mechanism of action of corilagin on schistosome egg-induced hepatic fibrosis via the IL-13Rα1 signaling pathway in M2 macrophages

Indexed as

AnimalsAnthelminticsBiomarkersCell LineGlucosidesHydrolyzable TanninsInterleukin-13 Receptor alpha1 SubunitKruppel-Like Factor 4Liver Cirrhosis, ExperimentalMacrophagesMaleMiceMice, Inbred C57BLPraziquantelRNA, Small InterferingSchistosomaAnthelminticsBiomarkerscorilaginGlucosidesHydrolyzable TanninsIl13ra1 protein, mouseInterleukin-13 Receptor alpha1 SubunitKlf4 protein, mouseKruppel-Like Factor 4PraziquantelRNA, Small InterferingcorilaginIL-13Rα1liver fibrosisM2 macrophageschistosome egg

Identifiers

PMID29094025
PMCPMC5651236
OpenAlexW2765500392

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.