Evidence map›Paper›PMID 29094019›Full record

ArticleAsia Pacific allergy2017

Serum 25-hydroxyvitamin D inversely associated with blood eosinophils in patients with persistent allergic rhinitis.

Hai-Yan Wu, Jin-Xiang Chen, Hui-Qin Tian, Xiu-Ling Zhang, Hai-Yan Bian, Lei Cheng

Open access · greenAbstract read
In one paragraph

Article in Asia Pacific allergy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Vitamin D and allergic diseases.Frontiers in immunology · 2024
    Review
  5. Article
  6. Article
  7. Article
  8. Vitamin D Deficiency and Interleukin Levels in Allergic Rhinitis: A Case-Control Study.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2022
    Article
  9. Article
  10. Vitamin D receptor gene polymorphisms in atopy.Immunity, inflammation and disease · 2021
    Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Hai-Yan WuDepartment of Otorhinolaryngology, The First Affiliated Hospital, Nanjing Medical University, Nanjing 210029, Jiangsu, China.
Jin-Xiang ChenDepartment of Otorhinolaryngology, Affiliated Jiangyin Hospital, Medical College of Southeast University, Jiangyin 214400, Jiangsu, China.
Hui-Qin TianDepartment of Otorhinolaryngology, The First Affiliated Hospital, Nanjing Medical University, Nanjing 210029, Jiangsu, China.
Xiu-Ling ZhangDepartment of Otorhinolaryngology, Affiliated Jiangyin Hospital, Medical College of Southeast University, Jiangyin 214400, Jiangsu, China.
Hai-Yan BianDepartment of Otorhinolaryngology, Affiliated Jiangyin Hospital, Medical College of Southeast University, Jiangyin 214400, Jiangsu, China.
Lei ChengDepartment of Otorhinolaryngology, The First Affiliated Hospital, Nanjing Medical University, Nanjing 210029, Jiangsu, China.
Nanjing Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe relationship between vitamin D and allergic rhinitis (AR) remains unclear. The present study investigated their association by examining serum 25-hydroxyvitamin D (25(OH)D) levels, blood eosinophils, and the expression of vitamin D receptors (VDR) on nasal mucosa in patients with AR.

methodsA total of 32 patients with persistent AR and 25 controls were enrolled in this study. Serum 25(OH)D levels were detected by enzyme-linked immunosorbent assay, and eosinophils in the peripheral blood were examined by an automated hematology system, while VDR expression on inferior turbinate mucosa was assessed by immunohistochemistry. Furthermore, the correlation of serum 25(OH)D levels with blood eosinophils in persistent AR was analyzed.

resultsNo significant difference in serum 25(OH)D levels was detected between the AR and control groups (

conclusionThese results suggest that the serum 25(OH)D might be inversely associated with blood eosinophils in patients with persistent AR. However, the relationship between vitamin D and AR still requires further clarification.

Indexed as

25-hydroxyvitamin DEosinophilsNasal mucosaRhinitis, allergicVitamin DVitamin D receptors

Identifiers

PMID29094019
PMCPMC5663749
OpenAlexW2765473720

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.