ArticleRSC advances2016
Precision Microfilters as an all in one System for Multiplex Analysis of Circulating Tumor Cells.
Article in RSC advances, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed.
- Trial
- Real-Time Therapy Response Monitoring Using Surface Biomarkers on Circulating Tumor Cells.Cancers · 2026Review
- Phenotyping and clinical utility of phagocytic polyploid giant cancer macrophages in blood.Cancer letters · 2025Article
- The integrated on-chip isolation and detection of circulating tumour cells.Sensors & diagnostics · 2024Review
- Comparison of sample preparation methods for rare cell isolation in microfluidic devices.Canadian journal of chemistry · 2022Article
- Real-Time Detection of Tumor Cells during Capture on a Filter Element Significantly Enhancing Detection Rate.Biosensors · 2021Article
- Integration of Lateral Filter Arrays with Immunoaffinity for Circulating-Tumor-Cell Isolation.Angewandte Chemie (International ed. in English) · 2019Article
- Blood-based biopsies-clinical utility beyond circulating tumor cells.Cytometry. Part A : the journal of the International Society for Analytical Cytology · 2018Article
- Microfabrication of Micropore Array for Cell Separation and Cell Assay.Micromachines · 2018Article
- 2.5-Dimensional Parylene C micropore array with a large area and a high porosity for high-throughput particle and cell separation.Microsystems & nanoengineering · 2018Article
- Circulating tumor markers: harmonizing the yin and yang of CTCs and ctDNA for precision medicine.Annals of oncology : official journal of the European Society for Medical Oncology · 2017Review
- Enrichment and Molecular Analysis of Breast Cancer Disseminated Tumor Cells from Bone Marrow Using Microfiltration.PloS one · 2017Article
- Multi-Phenotypic subtyping of circulating tumor cells using sequential fluorescent quenching and restaining.Scientific reports · 2016Article
- Circulating Cancer-Associated Macrophage-Like Cells Differentiate Malignant Breast Cancer and Benign Breast Conditions.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2016Article
- A cell transportation solution that preserves live circulating tumor cells in patient blood samples.BMC cancer · 2016Article
- Mitosis in circulating tumor cells stratifies highly aggressive breast carcinomas.Breast cancer research : BCR · 2016Article
Corrections and comments
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Authors and funding
12 authors.
Funding
Abstract
Enumeration of circulating tumor cells (CTCs) from cancer patient blood is an established diagnostic assay used to evaluate patient status as a singleplex test. However, in the coming age of personalized medicine, multiplex analysis of patient CTCs, including proteomic and genomic techniques, will have to be integrated with CTC isolation platform technologies. Advancements in microfabrication have demonstrated that CTCs can be isolated and analyzed using microfluidic lab-on-a-chip devices. However, to date, most microfluidic devices are either still in the development phase, not applicable to all clinical tests, or are not commercially available. To overcome these discrepancies, we describe an all-in-one device for the isolation and multiplexing of clinically applicable CTC assays. Microfilters present an ideal lab-on-a-chip platform for analysis of CTCs as non-toxic and inert materials allow for a multitude of tests from cell growth through clinical staining techniques, all without background interference. Lithographically fabricated microfilters, can be made with high porosity, precise pore dimensions, arrayed pore distribution, and optimized for CTC size-based isolation. In this study we describe microfilter use in isolation and
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.