Evidence map›Paper›PMID 29093660›Full record

ReviewFrontiers in neuroscience2017

Integration of Descending Command Systems for the Generation of Context-Specific Locomotor Behaviors.

Linda H Kim, Sandeep Sharma, Simon A Sharples, Kyle A Mayr, Charlie H T Kwok, Patrick J Whelan

Registry-linked trialAbstract readReview
In one paragraph

Review in Frontiers in neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04965727 (Deep Brain Stimulation of the Lateral Hypothalamus to Augment Motor Function of Patients With Spinal Cord Injury), which is not on this map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04965727 naunknown statusnot on this mapstarted 2021, after this paper: background citation

Deep Brain Stimulation of the Lateral Hypothalamus to Augment Motor Function of Patients With Spinal Cord Injury

TypeinterventionalSponsorJocelyne BlochRan2021 to 2026Enrolled3ConditionsDeep Brain Stimulation, Neuro: Spinal Cord InjuryArmsDevice implantation
3 · Its place in the literature

Who cites it

32 citing papers in PubMed.

  1. Article
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  9. Review
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  14. Review
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  16. Hyposmia may predict development of freezing of gait in Parkinson's disease.Journal of neural transmission (Vienna, Austria : 1996) · 2021
    Article
  17. Article
  18. Contributions of h- and NaFrontiers in cellular neuroscience · 2021
    Article
  19. Descending Dopaminergic Inputs to Reticulospinal Neurons Promote Locomotor Movements.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2020
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Linda H KimHotchkiss Brain Institute, University of Calgary, Calgary, AB, Canada.
Sandeep SharmaHotchkiss Brain Institute, University of Calgary, Calgary, AB, Canada.
Simon A SharplesHotchkiss Brain Institute, University of Calgary, Calgary, AB, Canada.
Kyle A MayrHotchkiss Brain Institute, University of Calgary, Calgary, AB, Canada.
Charlie H T KwokHotchkiss Brain Institute, University of Calgary, Calgary, AB, Canada.
Patrick J WhelanHotchkiss Brain Institute, University of Calgary, Calgary, AB, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Over the past decade there has been a renaissance in our understanding of spinal cord circuits; new technologies are beginning to provide key insights into descending circuits which project onto spinal cord central pattern generators. By integrating work from both the locomotor and animal behavioral fields, we can now examine context-specific control of locomotion, with an emphasis on descending modulation arising from various regions of the brainstem. Here we examine approach and avoidance behaviors and the circuits that lead to the production and arrest of locomotion.

Indexed as

approachaversiondescendinggoal-directedlocomotor behaviorsupraspinal

Identifiers

PMID29093660
PMCPMC5651258

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.