Evidence map›Paper›PMID 29093561›Full record

ArticleHypertension research : official journal of the Japanese Society of Hypertension2018

Hypertensive disorders of pregnancy: a strong risk factor for subsequent hypertension 5 years after delivery.

Asako Mito, Naoko Arata, Dongmei Qiu, Naoko Sakamoto, Atsuko Murashima, Atsuhiro Ichihara, Ryu Matsuoka, Akihiko Sekizawa, Yukihiro Ohya, Michihiro Kitagawa

Abstract read
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In one paragraph

Article in Hypertension research : official journal of the Japanese Society of Hypertension, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Hypertensive disorders of pregnancy: impact on future blood pressure and cardiovascular disease.Hypertension research : official journal of the Japanese Society of Hypertension · 2025
    Article
  5. Article
  6. Postpartum and interpregnancy care of women with a history of hypertensive disorders of pregnancy.Hypertension research : official journal of the Japanese Society of Hypertension · 2024
    Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Preeclampsia and Fetal Congenital Heart Defects.Current cardiology reviews · 2022
    Review
  14. Review
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Hypertensive disorders of pregnancy, obesity, and hypertension in later life by age group: a cross-sectional analysis.Hypertension research : official journal of the Japanese Society of Hypertension · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Asako MitoDivision of Maternal Medicine, Center for Maternal-Fetal-Neonatal and Reproductive Medicine, National Center for Child Health and Development, Tokyo, Japan.
Naoko ArataDivision of Maternal Medicine, Center for Maternal-Fetal-Neonatal and Reproductive Medicine, National Center for Child Health and Development, Tokyo, Japan.
Dongmei QiuDepartment of Drug Dependence Research, National Institute of Mental Health, National Center of Neurology and Psychiatry, Tokyo, Japan.
Naoko SakamotoDepartment of Epidemiologic Research, Faculty of Nursing, Toho University, Tokyo, Japan.
Atsuko MurashimaDivision of Maternal Medicine, Center for Maternal-Fetal-Neonatal and Reproductive Medicine, National Center for Child Health and Development, Tokyo, Japan.
Atsuhiro IchiharaDepartment of Medicine II, Endocrinology and Hypertension, Tokyo Women's Medical University, Tokyo, Japan.
Ryu MatsuokaDepartment of Obstetrics and Gynecology, Showa University School of Medicine, Tokyo, Japan.
Akihiko SekizawaDepartment of Obstetrics and Gynecology, Showa University School of Medicine, Tokyo, Japan.
Yukihiro OhyaDivision of Allergy, Department of Medical Subspecialties, National Center for Child Health and Development, Tokyo, Japan.
Michihiro KitagawaCenter for Maternal-Fetal-Neonatal and Reproductive Medicine, National Center for Child Health and Development, Tokyo, Japan.
National Center For Child Health and Development · JPShowa University · JPNational Center of Neurology and Psychiatry · JPToho University · JPTokyo Women's Medical University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hypertensive disorders of pregnancy are known to be a risk factor for future cardiovascular diseases. In contrast, there is a paucity of data on the not so distant future prognosis of hypertensive disorders of pregnancy. In the present study, we evaluated the incidence of the diseases causing cardiovascular problems (hypertension, diabetes mellitus, dyslipidemia and metabolic syndrome) 5 years after delivery in Japanese women with hypertensive disorders of pregnancy. We performed a double-cohort study and compared medical conditions between women with and without a history of hypertensive disorders of pregnancy. A total of 1513 women who participated in the cohort study were invited to undergo a medical checkup 5 years after the index delivery, of whom 829 responded. After excluding pregnant and lactating women at the time of examination, 25 women with hypertensive disorders of pregnancy and 746 control subjects were analyzed. The incidence of hypertension was significantly higher among women with hypertensive disorders of pregnancy than women who were normotensive during pregnancy (24.0 vs. 2.5%, P<0.001). They were also at an increased risk of subsequent hypertension 5 years after the index delivery, after adjusting for confounding factors such as age, body mass index, family history of hypertension and salt intake (odds ratio 7.1, 95% CI, 2.0-25.6, P<0.003). These is no significant difference in the incidence of diabetes mellitus, dyslipidemia and metabolic syndrome. In conclusion, hypertensive disorders of pregnancy are strong risk factors for subsequent hypertension only 5 years after delivery.

Indexed as

AdultCase-Control StudiesCohort StudiesDiabetes Mellitus, Type 2DietDyslipidemiasFemaleHumansHypertensionHypertension, Pregnancy-InducedIncidenceJapanMetabolic SyndromePre-EclampsiaPregnancyRisk Factors

Identifiers

PMID29093561
OpenAlexW2767117724

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.