Trial reportScientific reports2017
A Study of the Brain Functional Network of Post-Stroke Depression in Three Different Lesion Locations.
Trial report in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 32 citations in OpenAlex.
- Frequency-dependent alterations of degree centrality in patients with poststroke depression: a resting-state functional MRI study.Neuroreport · 2026Article
- Applications of ICF-Based Assessments and Interventions in Post-Stroke Rehabilitation: A Narrative Review.NeuroRehabilitation · 2026Review
- Cognitive and Spontaneous Brain Activity in Nonaddictive Smartphone Users Among Older Adults in China: Cross-Sectional Study.Journal of medical Internet research · 2025Article
- Post stroke depression: pathogenesis and molecular mechanisms of natural product-based interventions.Frontiers in pharmacology · 2025Review
- Effects of Manual Acupuncture Versus Sham Acupuncture in patients with Post-Stroke Depression: A Randomized Clinical Trial.Neurology and therapy · 2024Article
- Frequency specific alterations of the degree centrality in patients with acute basal ganglia ischemic stroke: a resting-state fMRI study.Brain imaging and behavior · 2024Article
- Naoxin'an capsules protect brain function and structure in patients with vascular cognitive impairment.Frontiers in pharmacology · 2023Article
- Article
- Ability of an altered functional coupling between resting-state networks to predict behavioral outcomes in subcortical ischemic stroke: A longitudinal study.Frontiers in aging neuroscience · 2022Article
- The White Matter Functional Abnormalities in Patients with Transient Ischemic Attack: A Reinforcement Learning Approach.Neural plasticity · 2022Article
- Understanding Why Post-Stroke Depression May Be the Norm Rather Than the Exception: The Anatomical and Neuroinflammatory Correlates of Post-Stroke Depression.Journal of clinical medicine · 2021Review
- The Local Brain Abnormalities in Patients With Transient Ischemic Attack: A Resting-State fMRI Study.Frontiers in neuroscience · 2019Article
- Altered Topology of the Structural Brain Network in Patients With Post-stroke Depression.Frontiers in neuroscience · 2019Article
- Ischemic Stroke in Pontine and Corona Radiata: Location Specific Impairment of Neural Network Investigated With Resting State fMRI.Frontiers in neurology · 2019Article
- Leveraging Spatial Information in Radiology Reports for Ischemic Stroke Phenotyping.AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational ScienceArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Research on the mechanism of post stroke depression (PSD) is the key way to improve the treatment of PSD. However, the functional brain network of PSD has not been entirely supported by the results of functional magnetic resonance imaging (fMRI) studies. The aims of this study are to investigate the brain response of PSD in three different lesions. The brain responses of the three PSD subgroups were similar. However, each subgroup had its own characteristics of the brain network. In the temporal lobe subgroup, the right thalamus had increased degree centrality (DC) values which were different from the other two subgroups. In the frontal lobe subgroup, the left dorsolateral prefrontal cortex, caudate, and postcentral gyrus had increased DC values which were different from the other two subgroups. The hemodynamic response of PSD indicates that PSD has activities of similar emotional networks, of which the negative network realizes its function through the limbic system and default mode network. The brain network has unique characteristics for different lesion locations. The neurological function of the lesion location, the compensatory mechanism of the brain, and the mechanism of integrity and locality of the brain are the important factors in the individual emotional network.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.