Evidence map›Paper›PMID 29093526›Full record

ArticleScientific reports2017

Spermine oxidase promotes bile canalicular lumen formation through acrolein production.

Takeshi Uemura, Tomokazu Takasaka, Kazuei Igarashi, Hiroshi Ikegaya

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Inhibition of Polyamine Catabolism Reduces Cellular Senescence.International journal of molecular sciences · 2023
    Article
  6. Article
  7. Review
  8. Polyamine Homeostasis in Development and Disease.Medical sciences (Basel, Switzerland) · 2021
    Review
  9. Article
  10. Discovery and antitumor evaluation of novel inhibitors of spermine oxidase.Journal of enzyme inhibition and medicinal chemistry · 2019
    Article
  11. Article
  12. Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Takeshi UemuraAmine Pharma Research Institute, 1-8-15 Inohana, Chuo-ku, Chiba, 260-0856, Japan. uemura@amine-pharma.com.
Tomokazu TakasakaDepartment of Forensic Medicine, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, 465 Kajii-cho, Kawaramachi-Hirokoji, Kamigyo-ku, Kyoto, 602-8566, Japan.
Kazuei IgarashiAmine Pharma Research Institute, 1-8-15 Inohana, Chuo-ku, Chiba, 260-0856, Japan.
Hiroshi IkegayaDepartment of Forensic Medicine, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, 465 Kajii-cho, Kawaramachi-Hirokoji, Kamigyo-ku, Kyoto, 602-8566, Japan.
Kyoto Prefectural University of Medicine · JPChiba University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Spermine oxidase (SMOX) catalyzes oxidation of spermine to generate spermidine, hydrogen peroxide (H

Indexed as

AcroleinActinsAldehydesAlkylationBile CanaliculiHep G2 CellsHumansOxidoreductases Acting on CH-NH Group DonorsPhosphorylationPolyamine OxidasePropylaminesProto-Oncogene Proteins c-aktPTEN Phosphohydrolase3-aminopropionaldehydeAcroleinActinsAldehydesOxidoreductases Acting on CH-NH Group DonorsPolyamine OxidasePropylaminesProto-Oncogene Proteins c-aktPTEN PhosphohydrolasePTEN protein, human

Identifiers

PMID29093526
PMCPMC5665972
OpenAlexW2766927655

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.