ArticleScientific reports2017
OCT Amplitude and Speckle Statistics of Discrete Random Media.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
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Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Signal-carrying speckle in optical coherence tomography: a methodological review on biomedical applications.Journal of biomedical optics · 2022Pooled it
- Achieving High-Precision Attenuation Coefficient Measurement in Optical Coherence Tomography.Journal of biophotonics · 2025Article
- Quantification of attenuation and speckle features from endoscopic OCT images for the diagnosis of human brain glioma.Scientific reports · 2024Article
- K-Space Approach in Optical Coherence Tomography: Rigorous Digital Transformation of Arbitrary-Shape Beams, Aberration Elimination and Super-Refocusing beyond Conventional Phase Correction Procedures.Sensors (Basel, Switzerland) · 2024Article
- Compression OCT-elastography combined with speckle-contrast analysis as an approach to the morphological assessment of breast cancer tissue.Biomedical optics express · 2023Article
- Accuracy and precision of depth-resolved estimation of attenuation coefficients in optical coherence tomography.Journal of biomedical optics · 2023Article
- Precision of attenuation coefficient measurements by optical coherence tomography.Journal of biomedical optics · 2022Article
- Local Burr distribution estimator for speckle statistics.Biomedical optics express · 2022Article
- Simulating scan formation in multimodal optical coherence tomography: angular-spectrum formulation based on ballistic scattering of arbitrary-form beams.Biomedical optics express · 2021Article
- Statistical analysis of corneal OCT speckle: a non-parametric approach.Biomedical optics express · 2021Article
- Speckle statistics of biological tissues in optical coherence tomography.Biomedical optics express · 2021Article
- Approximate image synthesis in optical coherence tomography.Biomedical optics express · 2021Article
- Bayesian analysis of depth resolved OCT attenuation coefficients.Scientific reports · 2021Article
- Article
- Noise and bias in optical coherence tomography intensity signal decorrelation.OSA continuum · 2020Article
- Signal averaging improves signal-to-noise in OCT images: But which approach works best, and when?Biomedical optics express · 2019Article
- Pilot feasibility study of in vivo intraoperative quantitative optical coherence tomography of human brain tissue during glioma resection.Journal of biophotonics · 2019Article
- Review of methods and applications of attenuation coefficient measurements with optical coherence tomography.Journal of biomedical optics · 2019Review
- Analysis of low-scattering regions in optical coherence tomography: applications to neurography and lymphangiography.Biomedical optics express · 2019Article
- Automatically Determining the Confocal Parameters From OCT B-Scans for Quantification of the Attenuation Coefficients.IEEE transactions on medical imaging · 2019Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Speckle, amplitude fluctuations in optical coherence tomography (OCT) images, contains information on sub-resolution structural properties of the imaged sample. Speckle statistics could therefore be utilized in the characterization of biological tissues. However, a rigorous theoretical framework relating OCT speckle statistics to structural tissue properties has yet to be developed. As a first step, we present a theoretical description of OCT speckle, relating the OCT amplitude variance to size and organization for samples of discrete random media (DRM). Starting the calculations from the size and organization of the scattering particles, we analytically find expressions for the OCT amplitude mean, amplitude variance, the backscattering coefficient and the scattering coefficient. We assume fully developed speckle and verify the validity of this assumption by experiments on controlled samples of silica microspheres suspended in water. We show that the OCT amplitude variance is sensitive to sub-resolution changes in size and organization of the scattering particles. Experimentally determined and theoretically calculated optical properties are compared and in good agreement.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.