Evidence map›Paper›PMID 29093458›Full record

ArticleScientific reports2017

Prevalence and genotype distribution of human papillomavirus in 961,029 screening tests in southeastern China (Zhejiang Province) between 2011 and 2015.

Xiao Chen, Haiou Xu, Wanwan Xu, Wenjie Zeng, Jinwei Liu, Qing Wu, Xiaofeng Zhao, Tang Jiang

Abstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. [Effectiveness of Different Testing Strategies Applied for Cervical Cancer Screening in Shuangliu District, Chengdu City].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2022
    Trial
  3. Article
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  10. Male Human Papillomavirus Infection and Genotyping in Turkey.Asian Pacific journal of cancer prevention : APJCP · 2023
    Article
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  12. Article
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  15. Prognostic value ofFrontiers in genetics · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Xiao ChenState Key Laboratory for Diagnosis and Treatment of Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Key Laboratory of Clinical In Vitro Diagnostic Techniques of Zhejiang Province, the First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang, 310003, China.
Haiou XuDepartment of Gynecology, Zhejiang Provincial People's Hospital, Hangzhou, Zhejiang, 310014, China.
Wanwan XuBengbu Medical College, Department of Gynecology, Zhejiang Provincial People's Hospital, Hangzhou, Zhejiang, 310014, China.
Wenjie ZengDepartment of Gynecology, Zhejiang Provincial People's Hospital, Hangzhou, Zhejiang, 310014, China.
Jinwei LiuDepartment of Gynecology, Zhejiang Provincial People's Hospital, Hangzhou, Zhejiang, 310014, China.
Qing WuDepartment of Gynecology, Zhejiang Provincial People's Hospital, Hangzhou, Zhejiang, 310014, China.
Xiaofeng ZhaoKey Laboratory of Tumor Molecular Diagnosis and Individualized Medicine of Zhejiang Province, Departments of Gynecology, Zhejiang Provincial People's Hospital, Hangzhou, Zhejiang, 310014, China. xfzhao1@163.com.
Tang JiangHangzhou Medical Laboratory of Dian Diagnostics, Hangzhou, Zhejiang, 310023, China. zsfchx80@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human papillomavirus infection plays a key role in the development of cervical cancer. To establish a foundation for HPV-based screening and vaccination programs, we investigated the HPV prevalence and genotypic distributions in Chinese women from Zhejiang Province. Between 2011 and 2015, a total of 961,029 samples from 2021 clinical hospitals were tested HPV genotype by a PCR-based hybridization gene chip assay, and 443,890 samples were evaluated cervical cytology by liquid-based cytology analysis. Our results showed that the positive rate for HPV was 20.54%, which ranged from 28.72% to 17.81% and varied by year of recruitment. Age-specific prevalence showed a "two-peak" pattern, with the ≤20-year-old group presenting the highest HPV infection rate, followed by 61-70-year-old group. Overall, the most prevalent genotypes were HPV16, 52 and 58. Additionally, the odds ratios for the prevalence of the HR-HPV, LR-HPV and HPV-negative groups with abnormal cytology were 12.56, 3.21 and 0.06, respectively. Among genotypes, HPV 16 has been found to have the highest OR, followed by HPV58, 18, 52. Here, we present data regarding the prevalence and type distribution of HPV infection, which can serve as valuable reference to guide nationwide cervical cancer screening and HPV vaccination programs.

Indexed as

AdolescentAdultAgedAge FactorsCervix UteriChinaFemaleGenotypeHumansMiddle AgedPapillomaviridaePapillomavirus InfectionsPrevalenceUterine Cervical NeoplasmsYoung Adult

Identifiers

PMID29093458
PMCPMC5665931

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.