Evidence map›Paper›PMID 29093402›Full record

ArticleInternal medicine (Tokyo, Japan)2018

Acute Cerebellar Ataxia Associated with Anti-glutamic Acid Decarboxylase Antibodies Mimicking Miller Fisher Syndrome.

Yoshitsugu Nakamura, Hideto Nakajima, Takafumi Hosokawa, Kazushi Yamane, Shimon Ishida, Fumiharu Kimura

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Yoshitsugu NakamuraDivision of Neurology, Department of Internal Medicine IV, Osaka Medical College, Japan.
Hideto NakajimaDivision of Neurology, Department of Internal Medicine IV, Osaka Medical College, Japan.
Takafumi HosokawaDivision of Neurology, Department of Internal Medicine IV, Osaka Medical College, Japan.
Kazushi YamaneDivision of Neurology, Department of Internal Medicine IV, Osaka Medical College, Japan.
Shimon IshidaDivision of Neurology, Department of Internal Medicine IV, Osaka Medical College, Japan.
Fumiharu KimuraDivision of Neurology, Department of Internal Medicine IV, Osaka Medical College, Japan.
Osaka Medical and Pharmaceutical University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We herein report the case of a 53-year-old man with cerebellar ataxia with anti-glutamic acid decarboxylase antibody (GAD-Ab) who mimicked Miller Fisher syndrome (MFS). He developed ophthalmoplegia, diplopia, and gait ataxia for one week. The serum and cerebrospinal fluid GAD-Ab titers were greatly increased, and the GAD-Ab index suggesting intrathecal antibody synthesis was elevated, while GQ1b-Ab was negative. After steroid pulse therapy and following prednisolone, his symptoms dramatically improved over the course of 11 months with the simultaneous decline of GAD-Ab titers. This case indicates that cerebellar ataxia with GAD-Ab can present with acute neurological findings mimicking MFS, and that steroid therapy has an excellent therapeutic effect.

Indexed as

AutoantibodiesCerebellar AtaxiaDiagnosis, DifferentialDiplopiaGait AtaxiaGlutamate DecarboxylaseHumansMaleMiddle AgedMiller Fisher SyndromeOphthalmoplegiaAutoantibodiesGlutamate Decarboxylaseacute onsetanti-GADataxiacorticosteroidMiller Fisher syndrome

Identifiers

PMID29093402
PMCPMC5820049
OpenAlexW2767103969

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.