ArticleProceedings. Biological sciences2017
Host-parasite fluctuating selection in the absence of specificity.
Article in Proceedings. Biological sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- Coevolution of host resistance and pathogen exploitation in a propagule-mediated infection model.PLoS computational biology · 2026Article
- The antagonistic coevolution between Pseudomonas sivasensis W-6 and the cold-adapted phage VW6S.Antonie van Leeuwenhoek · 2026Article
- The impact of sterility-mortality tolerance and recovery-transmission trade-offs on host-parasite coevolution.Proceedings. Biological sciences · 2024Article
- Host-parasite interactions in perpetual darkness: Macroparasite diversity in the cavefishZoological research · 2023Article
- How do fluctuating ecological dynamics impact the evolution of hosts and parasites?Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2023Review
- Microbial protection favors parasite tolerance and alters host-parasite coevolutionary dynamics.Current biology : CB · 2022Article
- Leapfrog dynamics in phage-bacteria coevolution revealed by joint analysis of cross-infection phenotypes and whole genome sequencing.Ecology letters · 2022Article
- Coevolutionary theory of hosts and parasites.Journal of evolutionary biology · 2022Review
- Spillover and genome selection of the gut parasiteFrontiers in cellular and infection microbiology · 2022Article
- An Ecologically Framed Comparison of The Potential for Zoonotic Transmission of Non-Human and Human-Infecting Species of Malaria Parasite.The Yale journal of biology and medicine · 2021Review
- The evolution of host resistance and parasite infectivity is highest in seasonal resource environments that oscillate at intermediate amplitudes.Proceedings. Biological sciences · 2020Article
- How long do Red Queen dynamics survive under genetic drift? A comparative analysis of evolutionary and eco-evolutionary models.BMC evolutionary biology · 2020Article
- Review
- Host-pathogen coevolution in the presence of predators: fluctuating selection and ecological feedbacks.Proceedings. Biological sciences · 2018Article
- Fueling Defense: Effects of Resources on the Ecology and Evolution of Tolerance to Parasite Infection.Frontiers in immunology · 2018Review
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Fluctuating selection driven by coevolution between hosts and parasites is important for the generation of host and parasite diversity across space and time. Theory has focused primarily on infection genetics, with highly specific 'matching-allele' frameworks more likely to generate fluctuating selection dynamics (FSD) than 'gene-for-gene' (generalist-specialist) frameworks. However, the environment, ecological feedbacks and life-history characteristics may all play a role in determining when FSD occurs. Here, we develop eco-evolutionary models with explicit ecological dynamics to explore the ecological, epidemiological and host life-history drivers of FSD. Our key result is to demonstrate for the first time, to our knowledge, that specificity between hosts and parasites is not required to generate FSD. Furthermore, highly specific host-parasite interactions produce unstable, less robust stochastic fluctuations in contrast to interactions that lack specificity altogether or those that vary from generalist to specialist, which produce predictable limit cycles. Given the ubiquity of ecological feedbacks and the variation in the nature of specificity in host-parasite interactions, our work emphasizes the underestimated potential for host-parasite coevolution to generate fluctuating selection.
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