Evidence map›Paper›PMID 29093082›Full record

ArticleJournal of virology2018

According to Hepatitis C Virus (HCV) Infection Stage, Interleukin-7 Plus 4-1BB Triggering Alone or Combined with PD-1 Blockade Increases TRAF1

Elia Moreno-Cubero, Dolores Subirá, Eduardo Sanz-de-Villalobos, Trinidad Parra-Cid, Antonio Madejón, Joaquín Miquel, Antonio Olveira, Alejandro González-Praetorius, Javier García-Samaniego, Juan-Ramón Larrubia

Open access · bronzeAbstract read
In one paragraph

Article in Journal of virology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Review
  7. Review
  8. T cell metabolism in chronic viral infection.Clinical and experimental immunology · 2019
    Review
  9. Liver-Mediated Adaptive Immune Tolerance.Frontiers in immunology · 2019
    Review
  10. Article
  11. Review
  12. TRAF1 Signaling in Human Health and Disease.Frontiers in immunology · 2018
    Review
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Elia Moreno-CuberoTranslational Hepatology Unit, Section of Digestive Diseases, Hospital Universitario de Guadalajara, Guadalajara, Spain.
Dolores SubiráService of Hematology, Hospital Universitario de Guadalajara, Guadalajara, Spain.
Eduardo Sanz-de-VillalobosTranslational Hepatology Unit, Section of Digestive Diseases, Hospital Universitario de Guadalajara, Guadalajara, Spain.
Trinidad Parra-CidService of Biochemistry, Hospital Universitario de Guadalajara, Guadalajara, Spain.
Antonio MadejónLiver Unit, Hospital Universitario La Paz, CIBERehd, IdiPaz, Madrid, Spain.
Joaquín MiquelTranslational Hepatology Unit, Section of Digestive Diseases, Hospital Universitario de Guadalajara, Guadalajara, Spain.
Antonio OlveiraLiver Unit, Hospital Universitario La Paz, CIBERehd, IdiPaz, Madrid, Spain.
Alejandro González-PraetoriusService of Microbiology, Hospital Universitario de Guadalajara, Guadalajara, Spain.
Javier García-SamaniegoLiver Unit, Hospital Universitario La Paz, CIBERehd, IdiPaz, Madrid, Spain.
Juan-Ramón LarrubiaTranslational Hepatology Unit, Section of Digestive Diseases, Hospital Universitario de Guadalajara, Guadalajara, Spain juan.larrubia@uah.es.ORCID http://orcid.org/0000-0002-6383-848X
Hospital Universitario de Guadalajara · ESHospital Universitario La Paz · ESUniversidad de Alcalá · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatitis C virus (HCV)-specific CD8

Indexed as

AgedCD8-Positive T-LymphocytesDisease ProgressionEpitopes, T-LymphocyteFemaleFlow CytometryGene ExpressionGenotypeHepacivirusHepatitis CHumansInterleukin-7Liver CirrhosisLymphocyte ActivationMaleMiddle AgedEpitopes, T-LymphocyteInterleukin-7Programmed Cell Death 1 ReceptorTNF Receptor-Associated Factor 1Tumor Necrosis Factor Receptor Superfamily, Member 94-1BBCD8 T cell responsehepatitis C virusIL-7immune checkpointimmunotherapyPD-1T cell exhaustionTGF-β1TRAF1

Identifiers

PMID29093082
PMCPMC5752940
OpenAlexW2766142027

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.