SynthesisJournal of the American Society of Nephrology : JASN2018
Genome-Wide Meta-Analysis Unravels Interactions between Magnesium Homeostasis and Metabolic Phenotypes.
Open access · bronzeAbstract readMeta-Analysis
In one paragraph
Synthesis in Journal of the American Society of Nephrology : JASN, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
2.9field-weighted citation impact, top 8% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 45 citations in OpenAlex.
- S-acylation and membrane localization of the small GTPase ARL15 are mediated by the Golgi S-acyltransferases ZDHHC7 and ZDHHC3.The Journal of biological chemistry · 2026Article
- The PACT Network: PRL, ARL, CNNM, and TRPM Proteins in Magnesium Transport and Disease.International journal of molecular sciences · 2025Review
- Genetic drivers of age-related changes in urinary magnesium excretion.Physiological genomics · 2024Article
- Genome-wide association study of serum magnesium in type 2 diabetes.Genes & nutrition · 2024Article
- Cleft palate and minor metabolic disturbances in a mouse global Arl15 gene knockout.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2023Article
- Physiology of a Forgotten Electrolyte-Magnesium Disorders.Advances in kidney disease and health · 2023Review
- UMOD and the architecture of kidney disease.Pflugers Archiv : European journal of physiology · 2022Review
- Arl15 upregulates the TGFβ family signaling by promoting the assembly of the Smad-complex.eLife · 2022Article
- Article
- Review
- The molecular appearance of native TRPM7 channel complexes identified by high-resolution proteomics.eLife · 2021Article
- ARL15 modulates magnesium homeostasis through N-glycosylation of CNNMs.Cellular and molecular life sciences : CMLS · 2021Article
- Clinical physiology of the kidney, electrolytes and lithiasis. The "old" meets the "new".Journal of nephrology · 2021Article
- Article
- Reduced Insulin Resistance Partly Mediated the Association of High Dietary Magnesium Intake with Less Metabolic Syndrome in a Large Chinese Population.Diabetes, metabolic syndrome and obesity : targets and therapy · 2020Article
- SLC41A1 is essential for magnesium homeostasis in vivo.Pflugers Archiv : European journal of physiology · 2019Article
- Ion channels and transporters in diabetic kidney disease.Current topics in membranes · 2019Review
- Oral herbal supplement containing magnesium sulfate improve metabolic control and insulin resistance in non-diabetic overweight patients: A randomized double blind clinical trial.Medical journal of the Islamic Republic of Iran · 2019Article
- Uromodulin regulates renal magnesium homeostasis through the ion channel transient receptor potential melastatin 6 (TRPM6).The Journal of biological chemistry · 2018Article
- Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
41 authors at 18 institutions in 9 countries.
Tanguy CorreInstitute of Social and Preventive Medicine.
Francisco J ArjonaDepartment of Physiology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands.
Caroline HaywardMedical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine.
Sonia YouhannaInstitute of Physiology, University of Zürich, Zurich, Switzerland.
Jeroen H F de BaaijDepartment of Physiology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands.
Hendrica BelgeInstitute of Physiology, University of Zürich, Zurich, Switzerland.
Nadine NägeleInstitute of Physiology, University of Zürich, Zurich, Switzerland.
Huguette DebaixInstitute of Physiology, University of Zürich, Zurich, Switzerland.
Maxime G BlanchardDepartment of Physiology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands.
Michela TragliaDivision of Genetics and Cell Biology, San Raffaele Scientific Institute, Milan, Italy.
Sarah E HarrisCentre for Cognitive Ageing and Cognitive Epidemiology.
Sheila UliviDepartment of Medical Genetics, Institute for Maternal and Child Health, Istituto di Ricovero e Cura a Carattere Scientifico "Burlo Garofolo," Trieste, Italy.
Rico RueediDepartment of Computational Biology, University of Lausanne, Lausanne, Switzerland.
David LamparterDepartment of Computational Biology, University of Lausanne, Lausanne, Switzerland.
Aurélien MacéInstitute of Social and Preventive Medicine.
Cinzia SalaDivision of Genetics and Cell Biology, San Raffaele Scientific Institute, Milan, Italy.
Stefania LenarduzziDepartment of Medical Genetics, Institute for Maternal and Child Health, Istituto di Ricovero e Cura a Carattere Scientifico "Burlo Garofolo," Trieste, Italy.
Belen PonteService of Nephrology and.
Menno PruijmService of Nephrology, University Hospital of Lausanne, Lausanne, Switzerland.
Daniel AckermannUniversity Clinic for Nephrology and Hypertension, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
Georg EhretDivision of Cardiology, Department of Internal Medicine Specialties, University Hospital of Geneva, Geneva, Switzerland.
Daniela BaptistaDivision of Cardiology, Department of Internal Medicine Specialties, University Hospital of Geneva, Geneva, Switzerland.
Ozren PolasekFaculty of Medicine, University of Split, Split, Croatia.
Igor RudanUsher Institute of Population Health Sciences and Informatics.
Toby W HurdMedical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine.
Nicholas D HastieMedical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine.
Veronique VitartMedical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine.
Geràrd WaeberDepartment of Medicine, Internal Medicine, and.
Zoltán KutalikInstitute of Social and Preventive Medicine.
Sven BergmannDepartment of Computational Biology, University of Lausanne, Lausanne, Switzerland.
Rosa Vargas-PoussouDepartment of Genetics, Hôpital Européen Georges Pompidou, Assistance Publique Hôpitaux de Paris, Paris, France.
Martin KonradDepartment of General Pediatrics, University Hospital Münster, Munster, Germany.
Paolo GaspariniDepartment of Medical, Surgical and Health Sciences, University of Trieste, Trieste, Italy; and.
Ian J DearyCentre for Cognitive Ageing and Cognitive Epidemiology.
John M StarrCentre for Cognitive Ageing and Cognitive Epidemiology.
Daniela TonioloDivision of Genetics and Cell Biology, San Raffaele Scientific Institute, Milan, Italy.
Peter VollenweiderDepartment of Medicine, Internal Medicine, and.
Joost G J HoenderopDepartment of Physiology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands.
René J M BindelsDepartment of Physiology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands.
Murielle BochudInstitute of Social and Preventive Medicine, olivier.devuyst@uzh.ch murielle.bochud@chuv.ch.
Olivier DevuystInstitute of Physiology, University of Zürich, Zurich, Switzerland; olivier.devuyst@uzh.ch murielle.bochud@chuv.ch.
University of Zurich · CHInstitute of Social and Preventive Medicine · CHMRC Human Genetics UnitUniversity of Lausanne · CHRadboud University Medical Center · NLSan Raffaele University of Rome · ITSIB Swiss Institute of Bioinformatics · CHIRCCS Materno Infantile Burlo Garofolo · ITRadboud University Nijmegen · NLAlzheimer Scotland · GBInstitute of Population and Public Health · CAMedical Research Council · GBMRC Institute of Genetics and Molecular Medicine · GBRadboud Institute for Molecular Life Sciences · NLUniversity of Bern · CHUniversity of Cape Town · ZAUniversity of Edinburgh · GBUniversity of Trieste · IT
Funding
Biotechnology and Biological Sciences Research Council BB/F019394/1Medical Research Council MC_PC_U127561128Medical Research Council MC_UU_00007/10Medical Research Council MR/K026992/1
Abstract
Magnesium (Mg
Indexed as
AdiposityADP-Ribosylation FactorsAnimalsGene-Environment InteractionGenome-Wide Association StudyGTP-Binding ProteinsHomeostasisHumansInsulinInsulin ResistanceKidneyMagnesiumMiceObesityPhenotypePolymorphism, Single NucleotideADP-Ribosylation Factorsarl15a protein, zebrafisharl15b protein, zebrafishARL15 protein, humanARL15 protein, mouseGTP-Binding ProteinsInsulinMagnesiumRNA, MessengerTRPM6 protein, humanTrpm6 protein, mouseTRPM Cation ChannelsZebrafish ProteinsGene-environment interactionGenetic determinantsMagnesium homeostasisMetabolic syndromeTubular transportzebrafish
Identifiers
What OpenQuestion holds
Textmetadata
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Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.