Evidence map›Paper›PMID 29092847›Full record

ArticleAmerican journal of physiology. Renal physiology2018

Measuring rat kidney glomerular number and size in vivo with MRI.

Edwin J Baldelomar, Jennifer R Charlton, Scott C Beeman, Kevin M Bennett

Abstract read
In one paragraph

Article in American journal of physiology. Renal physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed.

  1. Are noninvasive measurements of nephron number achievable in humans?Current opinion in nephrology and hypertension · 2026
    Review
  2. Article
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  7. Review
  8. Development and Use of Human RecombinantACS applied bio materials · 2024
    Article
  9. Article
  10. Article
  11. Article
  12. Chronic kidney disease in children: an update.Clinical kidney journal · 2023
    Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Edwin J BaldelomarUniversity of Hawaii at Manoa, Department of Physics , Honolulu, Hawaii.
Jennifer R CharltonUniversity of Virginia , Department of Pediatrics, Charlottesville, Virginia.
Scott C BeemanWashington University School of Medicine , Mallinckrodt Institute of Radiology, St. Louis, Missouri.
Kevin M BennettUniversity of Hawaii at Manoa, Department of Biology , Honolulu, Hawaii.

Funding

Comprehensive MRI-based evaluation of human renal microstructureR01DK111861 · NIDDK · UNIVERSITY OF VIRGINIA · PI BENNETT, KEVIN M, CHARLTON, JENNIFER R · 2017 to 2020
$1.8M
Noninvasive MRI techniques to detect pathology in murine models of renal diseaseR01DK110622 · NIDDK · WASHINGTON UNIVERSITY · PI BENNETT, KEVIN M, CHARLTON, JENNIFER R · 2017 to 2019
$1.0M
MR ADIPOSE-O2 QUANTIFICATION AND THE HYPOXIA-DRIVEN INSULIN RESISTANCE HYPOTHESISK01DK109119 · NIDDK · WASHINGTON UNIVERSITY · PI BEEMAN, SCOTT CHARLES · 2016 to 2020
$652k
NIDDK NIH HHS K01 DK109119NIDDK NIH HHS R01 DK110622NIDDK NIH HHS R01 DK111861
6 · The paper itself

Abstract

number is highly variable in humans and is thought to play an important role in renal health. Chronic kidney disease (CKD) is the result of too few nephrons to maintain homeostasis. Currently, nephron number can only be determined invasively or as a terminal assessment. Due to a lack of tools to measure and track nephron number in the living, the early stages of CKD often go unrecognized, preventing early intervention that might halt the progression of CKD. In this work, we present a technique to directly measure glomerular number ( N

Indexed as

AnimalsContrast MediaDisease Models, AnimalFerritinsImage Interpretation, Computer-AssistedImaging, Three-DimensionalKidney DiseasesKidney GlomerulusMagnetic Resonance ImagingMalePredictive Value of TestsRats, Sprague-DawleyReproducibility of ResultsSoftwareContrast MediaFerritinspolycationic ferritinCFE-MRIglomerular volumein vivomagnetic resonance imaging (MRI)nephron numberNglomVglom

Identifiers

PMID29092847
PMCPMC5899224

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.