ArticleNucleic acids research2018
SABIO-RK: an updated resource for manually curated biochemical reaction kinetics.
Article in Nucleic acids research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 97 papers.
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Who cites it
97 citing papers in PubMed.
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- Predicting Enzyme Turnover Numbers and Enabling Rational Enzyme Evolution.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Methods for the establishment of enzymatic mechanisms - from QM to ML.Chemical science · 2026Review
- Integrative machine learning approaches for enzyme kinetic parameter prediction.Briefings in bioinformatics · 2026Review
- WILDkCAT: extract, retrieve, and predict enzyme turnover numbers of constraint-based metabolic models.Bioinformatics (Oxford, England) · 2026Article
- AUKAT: Conditional VAE-Driven Augmentation and Neural Modeling of Enzyme Turnover Numbers.Biomolecules · 2026Article
- An enzyme-specific protein language model for catalytic property prediction.Nature communications · 2026Article
- A historical journey of metabolite-protein interaction discovery: from data harmonization to AI-driven prediction.Briefings in bioinformatics · 2026Review
- CBR-db: A Cheminformatic Database for Biochemical Reaction Analysis.ACS synthetic biology · 2026Article
- How far can you go? Extrapolating values of catalytic activity from known protein landscapes in natural and directed evolution.Chemical Society reviews · 2026Review
- A bifidobacterial enzyme orchestrates ecology and function of infant gut bacterial community.bioRxiv : the preprint server for biology · 2026Article
- EHMN 2026: A Thermodynamically Refined, SBML-Standardised Human Metabolic Network for Genome-Scale Analysis and QSP Integration.Metabolites · 2026Article
- KinForm: kinetics-informed feature optimised representation models for enzyme kNPJ systems biology and applications · 2026Article
- UniKineG: Unified-Coordinate Geometric Graphs Enable Robust Enzyme Kinetic Prediction.International journal of molecular sciences · 2026Article
- Enhancing kCommunications biology · 2026Article
- Advances in Machine Learning Models for Predicting Enzyme Kinetic Parameters.Journal of chemical information and modeling · 2026Review
- Machine learning for enzyme catalytic activity: current progress and future horizons.Briefings in bioinformatics · 2026Review
- MetaNetX: a bridge between metabolic resources for enhanced curation and multi-omics data harmonization.Nucleic acids research · 2026Article
- Open Enzyme Database: a community-wide repository for sharing enzyme data.Nucleic acids research · 2026Article
- GotEnzymes2: expanding coverage of enzyme kinetics and thermal properties.Nucleic acids research · 2026Article
37 more citing papers are in PubMed but not listed here.
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
SABIO-RK (http://sabiork.h-its.org/) is a manually curated database containing data about biochemical reactions and their reaction kinetics. The data are primarily extracted from scientific literature and stored in a relational database. The content comprises both naturally occurring and alternatively measured biochemical reactions and is not restricted to any organism class. The data are made available to the public by a web-based search interface and by web services for programmatic access. In this update we describe major improvements and extensions of SABIO-RK since our last publication in the database issue of Nucleic Acid Research (2012). (i) The website has been completely revised and (ii) allows now also free text search for kinetics data. (iii) Additional interlinkages with other databases in our field have been established; this enables users to gain directly comprehensive knowledge about the properties of enzymes and kinetics beyond SABIO-RK. (iv) Vice versa, direct access to SABIO-RK data has been implemented in several systems biology tools and workflows. (v) On request of our experimental users, the data can be exported now additionally in spreadsheet formats. (vi) The newly established SABIO-RK Curation Service allows to respond to specific data requirements.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.