ArticleJournal of hospital medicine2017
Association Between Anemia and Fatigue in Hospitalized Patients: Does the Measure of Anemia Matter?
Article in Journal of hospital medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Fatigue in Persons With Heart Failure: A Systematic Literature Review and Meta-Synthesis Using the Biopsychosocial Model of Health.Journal of cardiac failure · 2022Pooled it
- The effect of a single session of 30-min mindful breathing in reducing fatigue among patients with haematological cancer - a randomised controlled trial.BMC palliative care · 2021Trial
- The Association Between Hemoglobin Level and Cognitive Function in Older Adults During Hospitalization: A Prospective Observational Study.Health science reports · 2026Article
- Outcome analysis after cephalomedullary nail implantation in older adults and elderly patients with per-, sub- or intertrochanteric femur fractures.BMC research notes · 2025Article
- Effects of Jianpi therapy for cancer-related fatigue:a meta-analysis of randomized controlled trials.Frontiers in oncology · 2025Article
- The effect of red blood cell transfusion on fatigability after hospital discharge.Blood advances · 2020Observational
- Early and sustained improvement in fatigue-related quality of life following red blood cell transfusion in outpatients.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2020Article
- Fatigability: A new perspective on and patient-centered outcome measure for patients with anemia.American journal of hematology · 2020Observational
- Anti-TNF-Mediators of inflammation · 2019Article
- The effect of red-blood-cell transfusion on fatigue in hospitalized patients with anaemia.Vox sanguinis · 2018Observational
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
objectiveTo assess multiple Hb-based measures of anemia in hospitalized patients and test whether these are associated with fatigue.
designProspective observational study.
settingUrban, academic medical center. PATIENTS: Hospitalized general medicine patients, age =50 years, with any Hb < 9 g/dL. MEASUREMENTS: Measures of anemia were created for each patient based on the Hb values from their hospitalization (mean, median, minimum, maximum, admission, and discharge). Fatigue was measured using the Functional Assessment of Chronic Illness Therapy (FACIT)-Fatigue subscale.
resultsSeven hundred eighty-four patients participated. Minimum Hb was strongly associated with fatigue. Patients with a minimum Hb of < 8 g/dL had higher fatigue levels (mean FACIT [standard deviation] Hb < 7 g/dL: 25 [13], 7 g/ dL = Hb <8 g/dL: 25 [14] Hb =8 g/dL: 29 [14], P = 0.001) and were more likely to report high levels of fatigue (FACIT-Fatigue < 27) (56% vs 41%; P = 0.002). Mean Hb had a less robust association with fatigue than minimum Hb, and no other measure of Hb was associated with patients' fatigue levels.
conclusionsMinimum Hb is associated with fatigue while hospitalized and may help identify patients for interventions to address anemia-related fatigue.
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