ArticlePLoS neglected tropical diseases2017
After the epidemic: Zika virus projections for Latin America and the Caribbean.
Article in PLoS neglected tropical diseases, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 2 of them syntheses that pooled it.
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Who cites it
34 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- The Impact of Climate on Human Dengue Infections in the Caribbean.Pathogens (Basel, Switzerland) · 2024Pooled it
- Zika virus infection as a cause of congenital brain abnormalities and Guillain-Barré syndrome: A living systematic review.F1000Research · 2019Pooled it
- Understanding international travelers' health risk perceptions, preferences, and decisions: a segmentation analysis.Tropical diseases, travel medicine and vaccines · 2025Article
- Transfusion-transmitted infections: risks and mitigation strategies for Oropouche virus and other emerging arboviruses in Latin America and the Caribbean.Lancet regional health. Americas · 2025Review
- The economics of climate-sensitive infectious diseases affecting human health in Latin America and the Caribbean: a scoping review.BMJ global health · 2025Article
- Ubiquitin-like modifier-activating enzyme 1 interacts with Zika virus NS5 and promotes viral replication in the infected cell.The Journal of general virology · 2025Article
- Computational investigation of stochastic Zika virus optimal control model using Legendre spectral method.Scientific reports · 2024Article
- Synthesis of new series of quinoline derivatives with insecticidal effects on larval vectors of malaria and dengue diseases.Scientific reports · 2022Article
- Technological Transition in Higher Education Institution in the Time of Covid-19.Procedia computer science · 2022Article
- Yellow fever vaccine protects mice against Zika virus infection.PLoS neglected tropical diseases · 2021Article
- Scoping future outbreaks: a scoping review on the outbreak prediction of the WHO Blueprint list of priority diseases.BMJ global health · 2021Article
- Strategies for the Production of Soluble Interferon-AlphaLife (Basel, Switzerland) · 2021Article
- Assessing the reporting of Dengue, Chikungunya and Zika to the National Surveillance System in Colombia from 2014-2017: A Capture-recapture analysis accounting for misclassification of arboviral diagnostics.PLoS neglected tropical diseases · 2021Observational
- Modeling the association betweenCurrent research in parasitology & vector-borne diseases · 2021Article
- Rapid Response to Pandemic Threats: Immunogenic Epitope Detection of Pandemic Pathogens for Diagnostics and Vaccine Development Using Peptide Microarrays.Journal of proteome research · 2020Review
- Article
- Design of a Repellent Against Aedes aegypti (Diptera: Culicidae) Using in silico Simulations With AaegOBP1 Protein.Journal of medical entomology · 2020Article
- Article
- Cost-effectiveness of Prophylactic Zika Virus Vaccine in the Americas.Emerging infectious diseases · 2019Article
- The potential contribution of impaired brain glucose metabolism to congenital Zika syndrome.Journal of anatomy · 2019Review
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundZika is one of the most challenging emergent vector-borne diseases, yet its future public health impact remains unclear. Zika was of little public health concern until recent reports of its association with congenital syndromes. By 3 August 2017 ∼217,000 Zika cases and ∼3,400 cases of associated congenital syndrome were reported in Latin America and the Caribbean. Some modelling exercises suggest that Zika virus infection could become endemic in agreement with recent declarations from the The World Health Organisation. METHODOLOGY/PRINCIPAL
findingsWe produced high-resolution spatially-explicit projections of Zika cases, associated congenital syndromes and monetary costs for Latin America and the Caribbean now that the epidemic phase of the disease appears to be over. In contrast to previous studies which have adopted a modelling approach to map Zika potential, we project case numbers using a statistical approach based upon reported dengue case data as a Zika surrogate. Our results indicate that ∼12.3 (0.7-162.3) million Zika cases could be expected across Latin America and the Caribbean every year, leading to ∼64.4 (0.2-5159.3) thousand cases of Guillain-Barré syndrome and ∼4.7 (0.0-116.3) thousand cases of microcephaly. The economic burden of these neurological sequelae are estimated to be USD ∼2.3 (USD 0-159.3) billion per annum. CONCLUSIONS/SIGNIFICANCE: Zika is likely to have significant public health consequences across Latin America and the Caribbean in years to come. Our projections inform regional and federal health authorities, offering an opportunity to adapt to this public health challenge.
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