Evidence map›Paper›PMID 29091050›Full record

ArticlePhysical biology2017

Bottom-up synthetic biology: modular design for making artificial platelets.

Sagardip Majumder, Allen P Liu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Physical biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Biochemistry · 2022
    Article
  2. Review
  3. Review
  4. Review
  5. Engineering spatiotemporal organization and dynamics in synthetic cells.Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology · 2021
    Review
  6. Article
  7. Nanomedicines: A Potential Treatment for Blood Disorder Diseases.Frontiers in bioengineering and biotechnology · 2019
    Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Sagardip MajumderDepartment of Mechanical Engineering, University of Michigan, Ann Arbor, MI, United States of America.
Allen P LiuDepartment of Mechanical Engineering, University of Michigan, Ann Arbor, MI, United States of America.ORCID 0000-0002-0309-7018

Funding

Building artificial plateletsDP2HL117748 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LIU, ALLEN PO-CHIH · 2012 to 2012
$2.3M
NHLBI NIH HHS DP2 HL117748
6 · The paper itself

Abstract

Engineering artificial cells to mimic one or multiple fundamental cell biological functions is an emerging area of synthetic biology. Reconstituting functional modules from biological components in vitro is a challenging yet an important essence of bottom-up synthetic biology. Here we describe the concept of building artificial platelets using bottom-up synthetic biology and the four functional modules that together could enable such an ambitious effort.

Indexed as

Synthetic BiologyArtificial CellsBlood Platelets

Identifiers

PMID29091050
PMCPMC5832603

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.