Evidence map›Paper›PMID 29090425›Full record

ArticleJournal of molecular neuroscience : MN2017

Endogenous TRPV4 Expression of a Hybrid Neuronal Cell Line N18D3 and Its Utilization to Find a Novel Synthetic Ligand.

Sungjae Yoo, Seung-In Choi, Seul Lee, Jiho Song, Chungmi Yang, Sangsu Bang, Seung Up Kim, Kyung Hoon Min, Sun Wook Hwang

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of molecular neuroscience : MN, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 3 countries.

Sungjae YooDepartment of Biomedical Sciences, Korea University College of Medicine, #722 Moonsook Bldg., Inchon-Ro 73, Seongbuk-Gu, Seoul, 02841, South Korea.
Seung-In ChoiDepartment of Biomedical Sciences, Korea University College of Medicine, #722 Moonsook Bldg., Inchon-Ro 73, Seongbuk-Gu, Seoul, 02841, South Korea.
Seul LeeCollege of Pharmacy, Chung-Ang University, Heukseok-Ro 84, Dongjak-Gu, Seoul, 06974, South Korea.
Jiho SongCollege of Pharmacy, Chung-Ang University, Heukseok-Ro 84, Dongjak-Gu, Seoul, 06974, South Korea.
Chungmi YangDepartment of Biomedical Sciences, Korea University College of Medicine, #722 Moonsook Bldg., Inchon-Ro 73, Seongbuk-Gu, Seoul, 02841, South Korea.
Sangsu BangDepartment of Biomedical Sciences, Korea University College of Medicine, #722 Moonsook Bldg., Inchon-Ro 73, Seongbuk-Gu, Seoul, 02841, South Korea.
Seung Up KimMedical Research Institute, Chung-Ang University School of Medicine, Seoul, 06974, South Korea.
Kyung Hoon MinCollege of Pharmacy, Chung-Ang University, Heukseok-Ro 84, Dongjak-Gu, Seoul, 06974, South Korea. khmin@cau.ac.kr.
Sun Wook HwangDepartment of Biomedical Sciences, Korea University College of Medicine, #722 Moonsook Bldg., Inchon-Ro 73, Seongbuk-Gu, Seoul, 02841, South Korea. sunhwang@korea.ac.kr.ORCID http://orcid.org/0000-0001-8460-7480
Korea University · KRChung-Ang University · KRUniversity of British Columbia Hospital · CA

Funding

Korea Health technology R&D Project of Ministry of Health & Welfare HI15C2099National Research Foundation of Korea 2017M3C7A1025600National Research Foundation of Korea 2017R1A2B2001817
6 · The paper itself

Abstract

Primary sensory afferent neurons detect environmental and painful stimuli at their peripheral termini. A group of transient receptor potential ion channels (TRPs) are expressed in these neurons and constitute sensor molecules for the stimuli such as thermal, mechanical, and chemical insults. We examined whether a mouse sensory neuronal line, N18D3, shows the sensory TRP expressions and their functionality. In Ca

Indexed as

Action PotentialsAnimalsCells, CulturedDrug Partial AgonismHEK293 CellsHumansLigandsMembrane Transport ModulatorsMiceMice, Inbred ICRPrimary Cell CultureSensory Receptor CellsTRPV Cation ChannelsLigandsMembrane Transport ModulatorsTrpv4 protein, mouseTRPV Cation ChannelsMLV-0901N18D3Novel ligandSensory neuronsTRPV4

Identifiers

PMID29090425
OpenAlexW2765146544

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.