Evidence map›Paper›PMID 29090421›Full record

ArticleInfection2018

Alveolar echinococcosis in Germany, 1992-2016. An update based on the newly established national AE database.

Julian Schmidberger, Wolfgang Kratzer, Klaus Stark, Beate Grüner, Echinococcosis Working Group

Abstract read
PubMed Publisher
In one paragraph

Article in Infection, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. How can environmental fecal sampling supportFood and waterborne parasitology · 2026
    Article
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  6. Article
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  9. Helminths in Invasive Raccoons (Pathogens (Basel, Switzerland) · 2023
    Article
  10. [Spread and Development of Alveolar Echinococcosis in Germany, 1992-2018].Gesundheitswesen (Bundesverband der Arzte des Offentlichen Gesundheitsdienstes (Germany)) · 2023
    Article
  11. [Diagnostic delaying factors in hepatic alveolar echinococcosis].Deutsche medizinische Wochenschrift (1946) · 2023
    Article
  12. Article
  13. Article
  14. Article
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  20. Alveolar Echinococcosis in Children.Case reports in pediatrics · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Julian SchmidbergerCentral Ultrasound, Department of General Internal Medicine I, Medical Centre, University Hospital Ulm, Albert-Einstein-Allee 23, 89081, Ulm, Germany. julian.schmidberger@uniklinik-ulm.de.ORCID http://orcid.org/0000-0002-9960-9574
Wolfgang KratzerCentral Ultrasound, Department of General Internal Medicine I, Medical Centre, University Hospital Ulm, Albert-Einstein-Allee 23, 89081, Ulm, Germany.
Klaus StarkDepartment of Infectious Disease Epidemiology, Robert Koch Institute, Seestraße 10, 13353, Berlin, Germany.
Beate GrünerComprehensive Infectious Diseases Centre, Department of General Internal Medicine III, Medical Centre, University Hospital Ulm, Albert-Einstein-Allee 23, 89081, Ulm, Germany.
Echinococcosis Working Group
University Hospital Ulm · DERobert Koch Institute · DE

Funding

Deutsche Forschungsgemeinschaft No. 440/15
6 · The paper itself

Abstract

purposeAlveolar echinococcosis is a rare disease caused by the parasite Echinococcus multilocularis. The newly established national database should enable us to determine high-risk areas and evaluate the endemic levels.

methodsThe national database was implemented using SQL Workbench. We used EpiInfo™ software to display the prevalence of disease. Moran's I geodata analysis according to cluster and high risk areas was performed with GeoDa™. SAS Version 9.2 was used for the statistical analysis of the cases (n = 523).

resultsThe analysis showed a concentration of cases in Baden-Württemberg and Bavaria. Moran's I showed a heterogeneous case distribution throughout Germany (I = 0.208815, Z = 32.6175, p < 0.001). In the period from 1992 to 2016, the prevalence was 0.64/100,000 inhabitants in the whole of Germany, 2.18/100,000 inhabitants in Baden-Württemberg and 1.48/100,000 inhabitants in Bavaria. The analysis also revealed a difference between men and women, with a prevalence of 0.58/100,000 and 0.69/100,000, respectively. The analysis of spatial autocorrelation and possible risk areas showed that the southeast regions of Baden-Württemberg (I = 0.188514, Z = 11.3197, p < 0.001) and the southwest part of Bavaria (I = 0.176953, Z = 13.5144, p < 0.001) constitute the high risk areas.

conclusionsThe prevalence of disease is noticeably high in the Swabian Jura, the Bavarian Alps and the Alpine foothills. Raising awareness and educating doctors in high risk areas may prevent new cases and assist in earlier diagnosis.

Indexed as

AdultAgedAnimalsDatabases, FactualDisease NotificationEchinococcosisEchinococcus multilocularisFemaleGermanyHumansMaleMiddle AgedPrevalenceYoung AdultAlveolar echinococcosisDistributionEchinococcus multilocularisNational databasePrevalence

Identifiers

PMID29090421
OpenAlexW2767088551

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.