Evidence map›Paper›PMID 29090382›Full record

ArticleJournal of nephrology2018

Determinants of calcium and oxalate excretion in subjects with calcium nephrolithiasis: the role of metabolic syndrome traits.

Andrea Ticinesi, Angela Guerra, Franca Allegri, Antonio Nouvenne, Gianfranco Cervellin, Marcello Maggio, Fulvio Lauretani, Loris Borghi, Tiziana Meschi

Abstract read
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In one paragraph

Article in Journal of nephrology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Andrea TicinesiDepartment of Medicine and Surgery, University of Parma, Via Antonio Gramsci 14, 43126, Parma, Italy. andrea.ticinesi@unipr.it.ORCID http://orcid.org/0000-0001-9171-8592
Angela GuerraDepartment of Medicine and Surgery, University of Parma, Via Antonio Gramsci 14, 43126, Parma, Italy.
Franca AllegriDepartment of Medicine and Surgery, University of Parma, Via Antonio Gramsci 14, 43126, Parma, Italy.
Antonio NouvenneDepartment of Medicine and Surgery, University of Parma, Via Antonio Gramsci 14, 43126, Parma, Italy.
Gianfranco CervellinDipartimento d'Emergenza Urgenza e Area Medica Generale e Specialistica, Azienda Ospedaliero-Universitaria di Parma, Parma, Italy.
Marcello MaggioDepartment of Medicine and Surgery, University of Parma, Via Antonio Gramsci 14, 43126, Parma, Italy.
Fulvio LauretaniDepartment of Medicine and Surgery, University of Parma, Via Antonio Gramsci 14, 43126, Parma, Italy.
Loris BorghiDepartment of Medicine and Surgery, University of Parma, Via Antonio Gramsci 14, 43126, Parma, Italy.
Tiziana MeschiDepartment of Medicine and Surgery, University of Parma, Via Antonio Gramsci 14, 43126, Parma, Italy.
University of Parma · ITOspedale di Parma · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe association of metabolic syndrome (MetS) traits with urinary calcium (UCE) or oxalate excretion (UOE) is uncertain in calcium stone formers (CSFs). Our aim was to investigate this association in a large group of Caucasian CSFs.

methodsWe retrospectively reviewed data of CSFs evaluated at our Kidney Stone Clinic from 1984 to 2015. Data on body mass index (BMI), MetS traits defined according to international consensus, family history of urolithiasis, anti-hypertensive treatments, calcemia, renal function, and 24-h urinary profile of lithogenic risk were collected. The association between MetS traits and UCE or UOE was tested with multivariate linear regression models accounting for a long list of potential confounders.

resultsWe included 3003 CSFs, aged 44 ± 14 years. The prevalence of hypertension, diabetes, overweight (BMI ≥ 25 kg/m

conclusionsIn a large group of Caucasian CSFs, hypertension was the only MetS trait significantly associated with UCE, while no MetS trait was associated with oxalate excretion.

Indexed as

AdultCalciumComorbidityDyslipidemiasFemaleHumansHypercalciuriaHyperoxaluriaHypertensionItalyKidney CalculiMaleMiddle AgedOverweightOxalatesPrevalenceCalciumOxalatesDiabetesDyslipidemiaHypercalciuriaHypertensionObesityUrolithiasis

Identifiers

PMID29090382
OpenAlexW2767009617

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.