Evidence map›Paper›PMID 29090376›Full record

ArticleJournal of neurovirology2018

Aging alters voltage-gated calcium channels in prefrontal cortex pyramidal neurons in the HIV brain.

Christina E Khodr, Lihua Chen, Lena Al-Harthi, Xiu-Ti Hu

Abstract read
In one paragraph

Article in Journal of neurovirology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.6field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Christina E KhodrDepartment of Immunology and Microbiology, Rush University Medical Center, Cohn Research Building, Rm.414, 1735 W. Harrison Street, Chicago, IL, 60612, USA.
Lihua ChenDepartment of Immunology and Microbiology, Rush University Medical Center, Cohn Research Building, Rm.414, 1735 W. Harrison Street, Chicago, IL, 60612, USA.
Lena Al-HarthiDepartment of Immunology and Microbiology, Rush University Medical Center, Cohn Research Building, Rm.414, 1735 W. Harrison Street, Chicago, IL, 60612, USA.
Xiu-Ti HuDepartment of Immunology and Microbiology, Rush University Medical Center, Cohn Research Building, Rm.414, 1735 W. Harrison Street, Chicago, IL, 60612, USA. xiu-ti_hu@rush.edu.
Rush University Medical Center · US

Funding

Interplay between neuroprotective pathways, HIV, and astrocytesR01NS060632 · NINDS · RUSH UNIVERSITY MEDICAL CENTER · PI AL-HARTHI, LENA · 2008 to 2018
$4.9M
Interactive effects of Meth, HIV and cART on astrocyte/neuron functionR01DA044552 · NIDA · RUSH UNIVERSITY MEDICAL CENTER · PI HU, XIU-TI · 2017 to 2021
$2.9M
Electrophysiological mechanisms of HIV-mediated neuropathogenesisR01NS084817 · NINDS · RUSH UNIVERSITY MEDICAL CENTER · PI HU, XIU-TI · 2013 to 2017
$2.5M
mechanisms of HIV and drug abuse pathogenesis in CNSR01DA033966 · NIDA · RUSH UNIVERSITY MEDICAL CENTER · PI AL-HARTHI, LENA · 2012 to 2016
$1.7M
NIDA NIH HHS R01 DA033966NIDA NIH HHS R01 DA044552NINDS NIH HHS R01 NS060632NINDS NIH HHS R01 NS084817
6 · The paper itself

Abstract

We assessed firing and voltage-gated Ca

Indexed as

Action PotentialsAgingAIDS Dementia ComplexAnimalsCalciumCalcium Channels, L-TypeDisease Models, AnimalGene ExpressionHIV-1HumansMalePrefrontal CortexPyramidal CellsRatsRats, TransgenicCalciumCalcium Channels, L-TypeCalciumHANDHIVHIV-1 Tg ratL-channelMedial prefrontal cortex

Identifiers

PMID29090376
PMCPMC6492926
OpenAlexW2766528954

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.