Evidence map›Paper›PMID 29090363›Full record

ArticleJournal of biological physics2018

Calcium-axonemal microtubuli interactions underlie mechanism(s) of primary cilia morphological changes.

Vlado A Buljan, Manuel B Graeber, R M Damian Holsinger, Daniel Brown, Brett D Hambly, Edward J Delikatny, Vladimira R Vuletic, Xavier N Krebs, Ilijan B Tomas, John J Bohorquez-Florez and 2 more

Open access · greenAbstract read
In one paragraph

Article in Journal of biological physics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 3 countries.

Vlado A BuljanBrain Tumor Research Laboratories, Brain and Mind Center, Sydney Medical School and Faculty of Health Sciences, University of Sydney, Sydney, NSW, 2050, Australia. vlado.buljan@sydney.edu.au.
Manuel B GraeberBrain Tumor Research Laboratories, Brain and Mind Center, Sydney Medical School and Faculty of Health Sciences, University of Sydney, Sydney, NSW, 2050, Australia. manuel.graeber@sydney.edu.au.
R M Damian HolsingerLaboratory of Molecular Neuroscience and Dementia, Brain and Mind Center, Sydney Medical School, University of Sydney, Sydney, NSW, 2050, Australia.
Daniel BrownBrain Tumor Research Laboratories, Brain and Mind Center, Sydney Medical School and Faculty of Health Sciences, University of Sydney, Sydney, NSW, 2050, Australia.
Brett D HamblyDiscipline of Pathology, School of Medical Sciences, Sydney Medical School, Bosch Institute, University of Sydney, Sydney, NSW, 2006, Australia.
Edward J DelikatnyDepartment of Radiology, University of Pennsylvania, Philadelphia, PA, 19104, USA.
Vladimira R VuleticClinical Department of Neurology, UHC Rijeka, Medical Faculty Rijeka, Rijeka, Croatia.
Xavier N KrebsBrain Tumor Research Laboratories, Brain and Mind Center, Sydney Medical School and Faculty of Health Sciences, University of Sydney, Sydney, NSW, 2050, Australia.
Ilijan B TomasDepartment of Oncology and Radiotherapy, Medical Faculty, University 'Josip Juraj Strossmayer', 31000, Osijek, Croatia.
John J Bohorquez-FlorezBrain Tumor Research Laboratories, Brain and Mind Center, Sydney Medical School and Faculty of Health Sciences, University of Sydney, Sydney, NSW, 2050, Australia.
Guo Jun LiuAustralian Nuclear Sciences and Technology Organisation (ANSTO), The Bragg Institute and the Australian Synchrotron, Sydney, Australia.
Richard B BanatiBrain Tumor Research Laboratories, Brain and Mind Center, Sydney Medical School and Faculty of Health Sciences, University of Sydney, Sydney, NSW, 2050, Australia.
University of Sydney · AUAustralian Nuclear Science and Technology Organisation · AUAustralian Synchrotron · AUUniversity of Osijek · HRUniversity of Pennsylvania · USUniversity of Rijeka · HR

Funding

UNIVERSITY OF PENNSYLVANIA CAN CTR SUPPORT GRANTP30CA016520 · NCI · UNIVERSITY OF PENNSYLVANIA · PI Robert H. Vonderheide · 1985 to 2026
$222.3M
NCI NIH HHS P30 CA016520
6 · The paper itself

Abstract

We have used cell culture of astrocytes aligned within microchannels to investigate calcium effects on primary cilia morphology. In the absence of calcium and in the presence of flow of media (10 μL.s

Indexed as

AnimalsAxonemeBiological TransportCalciumCiliaMicrotubule-Associated ProteinsPaclitaxelProtein MultimerizationProtein Structure, QuaternaryRatsSpinal CordTRPP Cation ChannelsTubulinCalciumMicrotubule-Associated ProteinsPaclitaxelTRPP Cation ChannelsTubulinAxonemal microtubulesCalciumInteractionsMorphologyNonlinear dynamicsPrimary cilia

Identifiers

PMID29090363
PMCPMC5834999
OpenAlexW2766637560

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.