SynthesisEuropean journal of nutrition2018
A systematic review of vitamin D status in southern European countries.
Synthesis in European journal of nutrition, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 78 papers, 6 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
78 citing papers in PubMed, 6 syntheses or guidelines pooled it, 163 citations in OpenAlex.
- Pooled it
- Global and regional prevalence of vitamin D deficiency in population-based studies from 2000 to 2022: A pooled analysis of 7.9 million participants.Frontiers in nutrition · 2023Pooled it
- Pooled it
- Vitamin D status and blood pressure in children and adolescents: a systematic review of observational studies.Systematic reviews · 2021Pooled it
- Vitamin D Status and SARS-CoV-2 Infection and COVID-19 Clinical Outcomes.Frontiers in public health · 2021Pooled it
- Vitamin D in Breastfed Infants: Systematic Review of Alternatives to Daily Supplementation.Advances in nutrition (Bethesda, Md.) · 2020Pooled it
- Effect of Vitamin D-Enriched Gouda-Type Cheese Consumption on Biochemical Markers of Bone Metabolism in Postmenopausal Women in Greece.Nutrients · 2021Trial
- Pharmacokinetics of Oral Cholecalciferol in Healthy Subjects with Vitamin D Deficiency: A Randomized Open-Label Study.Nutrients · 2020Trial
- Article
- Update on Vitamin D Status and Seasonal Variation in a Non-Supplemented Population Living in a High Polluted Urban Area-A Cross-Sectional Study.Nutrients · 2026Article
- Vitamin D and calcium status in HYDRIA, Greece: associations with dietary and supplemental sources.European journal of nutrition · 2026Article
- Vitamin D Fortification Strategies and Policy Landscape in Selected European Countries.Nutrients · 2026Review
- Diet-Driven Epigenetic Alterations in Colorectal Cancer: From DNA Methylation and microRNA Expression to Liquid Biopsy Readouts.Biomedicines · 2026Review
- Genetic, Socioecological, and Health Research on Extreme Longevity in Semisupercentenarians and Supercentenarians: A Scoping Review.Journal of aging research · 2026Article
- Vitamin D deficiency among apparently healthy adults in northern China: behavioral correlates and an indoor-lifestyle framework.Frontiers in public health · 2026Article
- Rethinking Vitamin D Deficiency: Controversies and Practical Guidance for Clinical Management.Nutrients · 2025Review
- Article
- Maternal Vitamin D Status, Gestational Hypertension, and Preeclampsia: A Cross-Sectional Study in Urban Greece.Biomedicines · 2025Article
- Vitamin D3 supplementation in women practicing orthodox religious and intermittent fasting: A controlled study with formulation-specific effects.Metabolism open · 2025Article
- Pregnancy and Lactation-Associated Osteoporosis: Combined Pharmacological and Rehabilitative Management.Journal of functional morphology and kinesiology · 2025Article
18 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 4 institutions in 4 countries.
Funding
Abstract
purposeDespite an acknowledged dearth of data on serum 25-hydroxyvitamin D (25(OH)D) concentrations from Southern European countries, inter-country comparison is hampered by inconsistent data reporting. The purpose of the current study was to conduct a systematic literature review of available data on serum 25(OH)D concentrations and estimate vitamin D status in Southern European and Eastern Mediterranean countries, both at a population level and within key population subgroups, stratified by age, sex, season and country.
methodsA systematic review of the literature was conducted to identify and retrieve scientific articles reporting data on serum 25(OH)D concentration and/or vitamin D status following standard procedures.
resultsData were extracted from 107 studies, stratified by sex and age group, representing 630,093 individuals. More than one-third of the studies reported mean 25(OH)D concentrations below 50 nmol/L and ~ 10% reported mean serum 25(OH)D concentrations below 25 nmol/L. Overall, females, neonates/ infants and adolescents had the higher prevalence of poor vitamin D status. As expected, there was considerable variability between studies. Specifically, mean 25(OH)D ranged from 6.0 (in Italian centenarians) to 158 nmol/L (in elderly Turkish men); the prevalence of serum 25(OH)D < 50 nmol/L ranged from 6.8 to 97.9% (in Italian neonates).
conclusionsContrary to expectations, there was a high prevalence of low vitamin D status in the Southern Europe and the Eastern Mediterranean regions, despite abundant sunshine. These data further emphasize the need for strategies, such as fortification of foods with vitamin D and/or vitamin D supplementation, which will be tailored to the needs of specific population groups with higher risk of insufficiency or deficiency, to efficiently tackle the pandemic of hypovitaminosis D in Europe.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.