Evidence map›Paper›PMID 29090226›Full record

ArticleReports of biochemistry & molecular biology2017

Fifty Percent Ethanolic Extract of

Chikkavadaragudi Ramachandra Shobha, Vishwanath Prashant, Prashant Akila, Rangaswamy Chandini, Maduvanahalli Nataraj Suma, Hattur Basavanagowdappa

Open access · greenAbstract read
In one paragraph

Article in Reports of biochemistry & molecular biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. The Role ofInternational journal of environmental research and public health · 2019
    Review
  4. Article
  5. Antioxidative and Antimelanogenesis Effect ofEvidence-based complementary and alternative medicine : eCAM · 2019
    Article
  6. Nutrients · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Chikkavadaragudi Ramachandra ShobhaCenter of Excellence in Molecular Biology and Regenerative Medicine, Department of Biochemistry, JSS Medical College, Jagadguru Sri Shivarathreeswara University, Mysore, India.
Vishwanath PrashantCenter of Excellence in Molecular Biology and Regenerative Medicine, Department of Biochemistry, JSS Medical College, Jagadguru Sri Shivarathreeswara University, Mysore, India.
Prashant AkilaCenter of Excellence in Molecular Biology and Regenerative Medicine, Department of Biochemistry, JSS Medical College, Jagadguru Sri Shivarathreeswara University, Mysore, India.
Rangaswamy ChandiniCenter of Excellence in Molecular Biology and Regenerative Medicine, Department of Biochemistry, JSS Medical College, Jagadguru Sri Shivarathreeswara University, Mysore, India.
Maduvanahalli Nataraj SumaCenter of Excellence in Molecular Biology and Regenerative Medicine, Department of Biochemistry, JSS Medical College, Jagadguru Sri Shivarathreeswara University, Mysore, India.
Hattur BasavanagowdappaDepartment of Medicine, JSS Medical College, Jagadguru Sri Shivarathreeswara University, Mysore, India.
JSS Academy of Higher Education and Research · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNatural products have gained importance recently for the treatment of obesity and its complications, partly because of the side effects of modern drugs.Hence, we aimed to study and compare the effect of varying concentrations of

methods3T3-L1 pre-adipocytes were procured from the National Center for Cell Sciences, Pune, and cultured in Dulbecco's Modified Eagle's Media (DMEM) supplemented with 20% fetal bovine serum (FBS) and 1 mM L-glutamine. An ethanolic extract of

resultsThe 3T3-L1 pre-adipocytes treated with increasing concentrations of EEMC during (

conclusionThe data showed that the 50% EEMC is potent inhibitor of lipogenesis and stimulator of lipolysis in 3T3-L1 pre-adipocytes. Further analyses will be performed to determine the key antioxidant compound(s) in the extract by phenolic acid profiling using high performance liquid chromatography (HPLC). Also, the mechanism of action of EEMC on adipogenesis and adipolysis will be elucidated.

Indexed as

3T3-L1 pre-adipocytesAdipogenesisAdipolysisGlycerol releaseMomordicacharantiaOil red staining

Identifiers

PMID29090226
PMCPMC5643457
OpenAlexW2605526508

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.