Evidence map›Paper›PMID 29090191›Full record

ArticleJournal of comorbidity2017

Coronary heart disease risk in patients with schizophrenia: a Lebanese cross-sectional study.

Chadia Haddad, Souheil Hallit, Pascale Salameh, Tarek Bou-Assi, Marouan Zoghbi

Abstract read
In one paragraph

Article in Journal of comorbidity, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Chadia HaddadResearch Department, Psychiatric Hospital of the Cross, Jal Eddib, Lebanon.
Souheil HallitResearch Department, Psychiatric Hospital of the Cross, Jal Eddib, Lebanon.
Pascale SalamehFaculty of Pharmacy, Lebanese University, Beirut, Lebanon.
Tarek Bou-AssiDepartment of Laboratory Medicine, Psychiatric Hospital of the Cross, Jal Eddib, Lebanon.
Marouan ZoghbiResearch Department, Psychiatric Hospital of the Cross, Jal Eddib, Lebanon.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCoronary heart disease (CHD) is a leading cause of premature death in patients with schizophrenia. CHD risk in Lebanese patients with schizophrenia remains unknown.

objectivesTo (i) evaluate CHD risk of patients with schizophrenia in Lebanon; and (ii) detect the modifiable and non-modifiable factors affecting this risk.

methodsCross-sectional study of 329 patients with schizophrenia aged 20-75 years. Ten-year hard CHD risk was calculated using the Framingham risk score. A logistic regression was conducted taking the dichotomous hard CHD (<10% and ≥10%) as the dependent variable.

resultsTen-year hard CHD risk was low (<10%) in 60.8% of patients, intermediate (10-20%) in 31.6%, and high (>20%) in 7.6%. Multivariate analysis showed that the mean 10-year hard CHD risk was 8.76±6.92 (10.82±6.83 in men and 3.18±2.90 in women). Ten-year hard CHD risk was higher in patients with the metabolic syndrome (odds ratio [OR] 2.67, confidence interval [CI] 1.54-4.64), a longer duration of schizophrenia (OR 1.03, CI 1.01-1.05), a history of other medical illnesses (OR 2.02, CI 1.18-3.47), and in those participating in art therapy (OR 2.13, CI 1.25-3.64) or therapeutic education (OR 1.93, CI 0.93-4.01). Ten-year hard CHD risk was lower in patients receiving risperidone (OR 0.23, CI 0.08-0.68), any anti-epileptic (OR 0.41, CI 0.24-0.73), or any benzodiazepine (OR 0.33, CI 0.17-0.66) medication.

conclusionCHD is prevalent in patients with schizophrenia in Lebanon. Physicians are recommended to monitor the components of the metabolic syndrome to identify patients with increased risk of cardiovascular diseases.

Indexed as

antipsychoticscardiovascular diseaseFramingham risk scorelifestyle interventionsschizophrenia

Identifiers

PMID29090191
PMCPMC5556440

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