ArticleJournal of comorbidity2014
Competing risks of cancer mortality and cardiovascular events in individuals with multimorbidity.
Article in Journal of comorbidity, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 31 citations in OpenAlex.
- Impact of Chronic Kidney Disease Stages 3-5 on Mortality and Morbidity Outcomes in Patients with Esophageal Cancer: A Propensity-Score-Matched Cohort Study.Current oncology (Toronto, Ont.) · 2026Article
- Advancing care coordination to enhance shared care for complex cancer survivors in primary care (ACCESS-PC): protocol for a hybrid type 3 effectiveness-implementation trial.BMC primary care · 2026Article
- From Cardioprotection to Trial Design: Rethinking Cardiac Safety in Oncology.Current heart failure reports · 2026Review
- Health care cost trajectories among patients with cancer and cardiometabolic comorbidities over a decade including the pandemic period.Journal of managed care & specialty pharmacy · 2026Article
- Association of neighborhood economic trajectories and risk of mortality among older adults.Archives of public health = Archives belges de sante publique · 2026Article
- Calibration of cause-specific absolute risk for external validation using each cause-specific hazards model in the presence of competing events.Diagnostic and prognostic research · 2025Article
- Radio(chemo)therapy with curative intent for anal cancer - effectiveness and toxicity in elderly vs. younger patients.Frontiers in oncology · 2025Article
- Cancer and Heart Failure: Dangerous Liaisons.Journal of cardiovascular development and disease · 2024Review
- A COVID-19 Diagnosis Like an Avalanche Triggers a Series of Adverse Events but Saves a Life in the End.Healthcare (Basel, Switzerland) · 2023Article
- Cardiometabolic Comorbidities in Cancer Survivors:JACC. CardioOncology · 2022Review
- Cancer and heart disease: associations and relations.European journal of heart failure · 2019Review
- Obesity and cardiovascular risk in an oncology day ward population.Irish journal of medical science · 2019Article
- Mortality in Spain in the Context of the Economic Crisis and Austerity Policies.American journal of public health · 2019Article
- Competing Risk Analysis in Lung Cancer Patients Over 80 Years Old Undergoing Surgery.World journal of surgery · 2019Article
- Association between plasma lipid levels during acute coronary syndrome and long-term malignancy risk. The ABC-4* study on heart disease.BMC cardiovascular disorders · 2019Article
- Common risk factors for heart failure and cancer.Cardiovascular research · 2019Review
- Patterns of statin initiation and continuation in patients with breast or colorectal cancer, towards end-of-life.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCancer patients with cardiovascular and other comorbidities are at concurrent risk of multiple adverse outcomes. However, most treatment decisions are guided by evidence from single-outcome models, which may be misleading for multimorbid patients.
objectiveWe assessed the interacting effects of cancer, cardiovascular, and other morbidity burdens on the competing outcomes of cancer mortality, serious cardiovascular events, and other-cause mortality.
designWe analyzed a cohort of 6,500 adults with initial cancer diagnosis between 2001 and 2008, SEER 5-year survival ≥26%, and a range of cardiovascular risk factors. We estimated the cumulative incidence of cancer mortality, a serious cardiovascular event (myocardial infarction, coronary revascularization, or cardiovascular mortality), and other-cause mortality over 5 years, and identified factors associated with the competing risks of each outcome using cause-specific Cox proportional hazard models.
resultsFollowing cancer diagnosis, there were 996 (15.3%) cancer deaths, 328 (5.1%) serious cardiovascular events, and 542 (8.3%) deaths from other causes. In all, 4,634 (71.3%) cohort members had none of these outcomes. Although cancer prognosis had the greatest effect, cardiovascular and other morbidity also independently increased the hazard of each outcome. The effect of cancer prognosis on outcome was greatest in year 1, and the effect of other morbidity was greater in individuals with better cancer prognoses.
conclusionIn multimorbid oncology populations, comorbidities interact to affect the competing risk of different outcomes. Quantifying these risks may provide persons with cancer plus cardiovascular and other comorbidities more accurate information for shared decision-making than risks calculated from single-outcome models. Journal of Comorbidity 2014;4:29-36.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.