Evidence map›Paper›PMID 29090118›Full record

ReviewJournal of kidney cancer and VHL2017

The Risks of Renal Angiomyolipoma: Reviewing the Evidence.

Raouf M Seyam, Waleed K Alkhudair, Said A Kattan, Mohamed F Alotaibi, Hassan M Alzahrani, Waleed M Altaweel

Open access · diamondAbstract readReview
In one paragraph

Review in Journal of kidney cancer and VHL, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 52 citations in OpenAlex.

  1. Article
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  14. [Discussion on the surgical timing of rupture and hemorrhage of renal angiomyolipoma].Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences · 2024
    Article
  15. Angiomyolipoma during pregnancy: A forgotten risk factor for rupture and massive haemorrhage - A case report.Malaysian family physician : the official journal of the Academy of Family Physicians of Malaysia · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Raouf M SeyamDepartment of Urology, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia.
Waleed K AlkhudairDepartment of Urology, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia.
Said A KattanDepartment of Urology, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia.
Mohamed F AlotaibiDepartment of Urology, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia.
Hassan M AlzahraniDepartment of Urology, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia.
Waleed M AltaweelDepartment of Urology, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia.
King Faisal Specialist Hospital & Research Centre · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Renal angiomyolipoma (RAML), though a rare benign tumor, may impose a significant morbidity or even mortality due to its unique characteristics and the complications subsequent to its treatment. The classic tumor variant is composed of smooth muscular, vascular, and fatty components. The most straightforward diagnosis is when the fat component is abundant and gives a characteristic appearance on different imaging studies. In fat-poor lesions, however, the diagnosis is difficult and presumed a renal cell carcinoma. Yet, some variants of RAML, though rare, express an aggressive behavior leading to metastasis and mortality. The challenge lies in the early detection of benign variants and identifying aggressive lesions for proper management. Another challenge is when the vascular tissue component predominates and poses a risk of hemorrhage that may extend to the retroperitoneum in a massive life-threatening condition. The predicament here is to identify the characteristics of tumors at risk of bleeding and provide a prophylactic treatment. According to the clinical presentation, different treatment modalities, prophylactic or therapeutic, are available that span the spectrum of observation, embolization, or surgery. Renal impairment may result from extensive tumor burden or as a complication of the management itself. Improvement of diagnostic techniques, super-selective embolization, nephron-sparing surgery, and late treatment with the mammalian target of rapamycin inhibitors have provided more effective and safe management strategies. In this review, we examine the evidence pertaining to the risks imposed by RAML to the patients and identify merits and hazards associated with different treatment modalities.

Indexed as

angiomyolipomaembolizationhemorrhagekidneynephrectomy

Identifiers

PMID29090118
PMCPMC5644357
OpenAlexW2766826949

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.