Evidence map›Paper›PMID 29090026›Full record

ArticleMaedica2017

Vitamin D Receptor Gene Haplotype and Late-Onset Obesity in Iranian Azeri Turkish Women.

Morteza Bagheri, Fatemeh Bahadori, Shahsanam Gheibi, Tahereh Behrooz Lak, Zahra Kuse-Lu, Zahra Sahebozamani, Isa Abdi-Rad

Abstract read
PubMed Full text at PMC
In one paragraph

Article in Maedica, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.

  1. Vitamin D Receptor Polymorphisms Associated with Susceptibility to Obesity: A Meta-Analysis.Medical science monitor : international medical journal of experimental and clinical research · 2019
    Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Morteza BagheriMaternal and Childhood Obesity Research Center, Urmia University of Medical Sciences, Urmia, Iran.
Fatemeh BahadoriMaternal and Childhood Obesity Research Center, Urmia University of Medical Sciences, Urmia, Iran.
Shahsanam GheibiMaternal and Childhood Obesity Research Center, Urmia University of Medical Sciences, Urmia, Iran.
Tahereh Behrooz LakMaternal and Childhood Obesity Research Center, Urmia University of Medical Sciences, Urmia, Iran.
Zahra Kuse-LuMaternal and Childhood Obesity Research Center, Urmia University of Medical Sciences, Urmia, Iran.
Zahra SahebozamaniMaternal and Childhood Obesity Research Center, Urmia University of Medical Sciences, Urmia, Iran.
Isa Abdi-RadCellular and Molecular Research Center, Urmia University of Medical Sciences, Urmia, Iran.
Urmia University of Medical SciencesUrmia University · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionA large body of literature has revealed the association between vitamin D3-VDR complex and obesity. The aim of the present study was to survey the rate of the VDR polymorphisms in obese women and to determine whether there may be an association between VDR BsmI and Tru9I haplotypes and obesity in Iranian Azeri Turkish women. MATERIAL AND

methods65 Iranian Azeri Turkish women were enrolled in the study and PCR amplification and direct sequencing of PCR products were used for genotypings.

resultsThe findings of this study showed that VDR BsmIG allele, VDR BsmI G/G genotype, VDR BsmI A/A genotype, Tru9IA allele and Tru9I A/A genotype were more frequent in obese women compared to controls. The frequency of VDR BsmIG/Tru9IA (GA), VDR BsmIG/Tru9IG (GG), VDR BsmIA/Tru9IG (AG), and VDR BsmIA/Tru9IA (AA) haplotypes were 19.74%, 42.11%, 38.16% and 0% in cases, and 11.11%, 40.74%, 42.59 and 5.56% in controls. Statistically significant differences were found between cases and controls regarding the VDR AA haplotype (P=0.03).

conclusionsOur findings demonstrated that the VDR AA haplotype frequency was significantly lower in subjects with obesity compared with normal controls. This study shows that the VDR AA haplotype is significantly associated with a decreased risk of obesity in the tested group. This report is the first of its kind in the West Azerbaijani population.

Identifiers

PMID29090026
PMCPMC5649038
OpenAlexW2810304987

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.