Evidence map›Paper›PMID 29089990›Full record

ArticleNeural regeneration research2017

Therapeutic efficacy and safety of various botulinum toxin A doses and concentrations in spastic foot after stroke: a randomized controlled trial.

Jiang Li, Ru Zhang, Bo-Li Cui, Yong-Xiang Zhang, Guang-Tao Bai, Si-Shan Gao, Wen-Jian Li

Open access · goldAbstract read
In one paragraph

Article in Neural regeneration research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.2field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Observational
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Jiang LiAffiliated Hospital of Qingdao University, Qingdao, Shandong Province, China.
Ru ZhangAffiliated Hospital of Qingdao University, Qingdao, Shandong Province, China.
Bo-Li CuiAffiliated Hospital of Qingdao University, Qingdao, Shandong Province, China.
Yong-Xiang ZhangAffiliated Hospital of Qingdao University, Qingdao, Shandong Province, China.
Guang-Tao BaiAffiliated Hospital of Qingdao University, Qingdao, Shandong Province, China.
Si-Shan GaoDepartment of Neurology, Traditional Medicine Hospital of Huangdao District, Qingdao, Shandong Province, China.
Wen-Jian LiAffiliated Hospital of Qingdao University, Qingdao, Shandong Province, China.ORCID 0000-0002-7731-4812
Qingdao University · CNAffiliated Hospital of Qingdao University · CNJimo District Qingdao Hospital of Traditional Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

No recommended guidelines currently exist for the therapeutic concentration or dose of botulinum toxin type A (BTXA) injected into the muscle to treat limb spasticity. Therefore, in this randomized controlled trial, we explored the safety and efficacy of two concentrations and two doses of BTXA in the treatment of spastic foot after stroke to optimize this treatment in these patients. Eligible patients (

Indexed as

botulinum toxin type Afoot dropfoot spasmsfoot varusnerve regenerationneural regenerationstrokewalking function

Identifiers

PMID29089990
PMCPMC5649465
OpenAlexW2757210360

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.