Evidence map›Paper›PMID 29089893›Full record

ArticleFrontiers in pharmacology2017

Artemisinin: A Panacea Eligible for Unrestrictive Use?

Dong-Sheng Yuan, Yan-Ping Chen, Li-Li Tan, Shui-Qing Huang, Chang-Qing Li, Qi Wang, Qing-Ping Zeng

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.5field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. The potential role of sesquiterpene lactones isolated from medicinal plants in the treatment of the metabolic syndrome - A review.South African journal of botany : official journal of the South African Association of Botanists = Suid-Afrikaanse tydskrif vir plantkunde : amptelike tydskrif van die Suid-Afrikaanse Genootskap van Plantkundiges · 2020
    Review
  7. Artemether Regulates Metaflammation to Improve Glycolipid Metabolism in db/db Mice.Diabetes, metabolic syndrome and obesity : targets and therapy · 2020
    Article
  8. Article
  9. Review
  10. Assessment of Artemisinin Contents in SelectedMedicines (Basel, Switzerland) · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Dong-Sheng YuanClinical Pharmacology Institute, Guangzhou University of Chinese Medicine, Guangzhou, China.
Yan-Ping ChenTropical Medicine Institute, Guangzhou University of Chinese Medicine, Guangzhou, China.
Li-Li TanTropical Medicine Institute, Guangzhou University of Chinese Medicine, Guangzhou, China.
Shui-Qing HuangBasic Medical Science College, Guangzhou University of Chinese Medicine, Guangzhou, China.
Chang-Qing LiTropical Medicine Institute, Guangzhou University of Chinese Medicine, Guangzhou, China.
Qi WangClinical Pharmacology Institute, Guangzhou University of Chinese Medicine, Guangzhou, China.
Qing-Ping ZengTropical Medicine Institute, Guangzhou University of Chinese Medicine, Guangzhou, China.
Guangzhou University of Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although artemisinin has been used as anti-malarial drug, accumulating evidence on the extended therapeutic potential of artemisinin emerges. Apart from anti-malaria and anti-tumor, artemisinin can also exert beneficial effects on some metabolic disorders, such as obesity, diabetes, and aging-related diseases. However, whether artemisinin should be applied to treatment of the wide-spectrum diseases is debating. Here, we discuss the predisposition of a raised risk of malarial resistance to artemisinin from consideration of the multi-target and non-specific features of artemisinin.

Indexed as

artemisininmalarial resistancemulti-targetrestrictive usewide-spectrum

Identifiers

PMID29089893
PMCPMC5651041
OpenAlexW2766805981

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.