Evidence map›Paper›PMID 29089822›Full record

ArticleKorean journal of radiology

Impact of Liver Fibrosis and Fatty Liver on T1rho Measurements: A Prospective Study.

Shuangshuang Xie, Qing Li, Yue Cheng, Yu Zhang, Zhizheng Zhuo, Guiming Zhao, Wen Shen

Open access · hybridAbstract read
In one paragraph

Article in Korean journal of radiology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Multiparametric quantitative magnetic resonance imaging of skeletal muscle in CKD.American journal of physiology. Renal physiology · 2025
    Article
  7. A comparison of T1ρ with native T1 and T2 mapping for detecting edema in takotsubo cardiomyopathy.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2025
    Article
  8. Article
  9. Article
  10. TJournal of clinical medicine · 2022
    Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Volumetric multicomponent TMagnetic resonance in medicine · 2020
    Article
  17. TNMR in biomedicine · 2020
    Article
  18. Article
  19. Article
  20. Topics on quantitative liver magnetic resonance imaging.Quantitative imaging in medicine and surgery · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Shuangshuang XieDepartment of Radiology, Tianjin First Center Hospital, Tianjin 300192, China.
Qing LiDepartment of Radiology, Tianjin First Center Hospital, Tianjin 300192, China.
Yue ChengDepartment of Radiology, Tianjin First Center Hospital, Tianjin 300192, China.
Yu ZhangClinical Science, Philips Healthcare, Beijing 100600, China.
Zhizheng ZhuoClinical Science, Philips Healthcare, Beijing 100600, China.
Guiming ZhaoDepartment of Hepatology, Tianjin Second People's Hospital, Tianjin 300192, China.
Wen ShenDepartment of Radiology, Tianjin First Center Hospital, Tianjin 300192, China.
Tianjin Medical University · CNPhilips (China) · CNTianjin First Center Hospital · CNTianjin People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate the liver T1rho values for detecting fibrosis, and the potential impact of fatty liver on T1rho measurements. MATERIALS AND

methodsThis study included 18 healthy subjects, 18 patients with fatty liver, and 18 patients with liver fibrosis, who underwent T1rho MRI and mDIXON collections. Liver T1rho, proton density fat fraction (PDFF) and T2* values were measured and compared among the three groups. Receiver operating characteristic (ROC) curve analysis was performed to evaluate the T1rho values for detecting liver fibrosis. Liver T1rho values were correlated with PDFF, T2* values and clinical data.

resultsLiver T1rho and PDFF values were significantly different (

conclusionT1rho MRI is useful for noninvasive detection of liver fibrosis, and may not be affected with the presence of fatty liver.

Indexed as

Magnetic Resonance ImagingAdultAgedArea Under CurveBody Mass IndexFemaleHealthy VolunteersHumansImage Processing, Computer-AssistedLiver CirrhosisMaleMiddle AgedNon-alcoholic Fatty Liver DiseaseProspective StudiesROC CurveSensitivity and SpecificityFatty liverHepatic steatosisLiver fibrosisLiver stiffnessMagnetic resonance imagingT1rho

Identifiers

PMID29089822
PMCPMC5639155
OpenAlexW2763340450

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.