Evidence map›Paper›PMID 29089807›Full record

ArticleCurrent oncology (Toronto, Ont.)2017

The clinical significance of occult gynecologic primary tumours in metastatic cancer.

M B Hannouf, E Winquist, S M Mahmud, M Brackstone, S Sarma, G Rodrigues, P K Rogan, J S Hoch, G S Zaric

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Current oncology (Toronto, Ont.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 82% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 3 countries.

M B HannoufDepartment of Epidemiology and Biostatistics, Schulich School of Medicine and Dentistry, Western University, London, ON.
E WinquistDepartment of Oncology, Schulich School of Medicine and Dentistry, Western University, London, ON.
S M MahmudDepartment of Community Health Sciences, College of Medicine, Faculty of Health Sciences, University of Manitoba, Winnipeg, MB.
M BrackstoneDepartment of Oncology, Schulich School of Medicine and Dentistry, Western University, London, ON.
S SarmaDepartment of Epidemiology and Biostatistics, Schulich School of Medicine and Dentistry, Western University, London, ON.
G RodriguesDepartment of Epidemiology and Biostatistics, Schulich School of Medicine and Dentistry, Western University, London, ON.
P K RoganDepartment of Oncology, Schulich School of Medicine and Dentistry, Western University, London, ON.
J S HochInstitute of Health Policy Management and Evaluation, University of Toronto, Toronto, ON.
G S ZaricDepartment of Epidemiology and Biostatistics, Schulich School of Medicine and Dentistry, Western University, London, ON.
Western University · CAManitoba Health · CASt. Michael's Hospital · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveWe estimated the frequency of occult gynecologic primary tumours (gpts) in patients with metastatic cancer from an uncertain primary and evaluated the effect on disease management and overall survival (os).

methodsWe used Manitoba administrative health databases to identify all patients initially diagnosed with metastatic cancer during 2002-2011. We defined patients as having an "occult" primary tumour if the primary was classified at least 6 months after the initial diagnosis. Otherwise, we considered patients to have "obvious" primaries. We then compared clinicopathologic and treatment characteristics and 2-year os for women with occult and with obvious gpts. We used Cox regression adjustment and propensity score methods to assess the effect on os of having an occult gpt.

resultsAmong the 5953 patients diagnosed with metastatic cancer, occult primary tumours were more common in women (

conclusionsIn women with metastatic cancer from an uncertain primary, gpts constitute the largest clinical entity. Accurate diagnosis of occult gpts early in the course of metastatic cancer might lead to more effective treatment decisions and improved survival outcomes.

Indexed as

Cohort studiesdata linkagegynecologic cancersmatched groupsmetastasisoccult primary neoplasmspropensity score

Identifiers

PMID29089807
PMCPMC5659161
OpenAlexW2766414073

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.