Evidence map›Paper›PMID 29089780›Full record

ArticleClinical, cosmetic and investigational dermatology2017

Tailored botulinum toxin type A injections in aesthetic medicine: consensus panel recommendations for treating the forehead based on individual facial anatomy and muscle tone.

Javier Anido, Daniel Arenas, Cristina Arruabarrena, Alfonso Domínguez-Gil, Carlos Fajardo, Mar Mira, Javier Murillo, Natalia Ribé, Helga Rivera, Sofia Ruiz Del Cueto and 2 more

Abstract read
In one paragraph

Article in Clinical, cosmetic and investigational dermatology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

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  16. [New botulinum toxins for aesthetic dermatology : A comprehensive review].Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete · 2021
    Review
  17. Article
  18. COMMENTARY ON BOTULINUM TOXIN INJECTIONS: A CALL FOR IMPROVED ACCURACY.The Journal of clinical and aesthetic dermatology · 2020
    Review
  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Javier AnidoA-Clinic, Madrid.
Daniel ArenasHospital Cruz Roja, Madrid.
Cristina ArruabarrenaClinic Cristina Arruabarrena, San Sebastiá.
Alfonso Domínguez-GilSalamanca University, Salamanca.
Carlos FajardoClinic Fajardo, Malaga.
Mar MiraClinic Mira+Cueto, Madrid.
Javier MurilloClinic CIR, Seville.
Natalia RibéInstitute Natalia Ribé, Barcelona.
Helga RiveraClinic Helga Rivera, Vigo, Spain.
Sofia Ruiz Del CuetoClinic Mira+Cueto, Madrid.
Helder SilvestreClinic Europa, Lisbon, Portugal.
Marisa TiradoClinic Derma Alemar, Castellón, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFacial lines and wrinkles are strongly influenced by individual differences in anatomy and muscle activity and no single injection protocol will suit all patients. However, there is only limited information in the published literature on how to develop a tailored approach to botulinum toxin treatment.

methodsAn expert panel of physicians was convened to establish a consensus on developing an individualized approach to treatment of the forehead with incobotulinumtoxinA. Separate treatment protocols were developed for men and women and subdivided by background level of muscle activity: kinetic, hyperkinetic, and hypertonic. Each muscle tone category was then further subdivided to take account of individual characteristics that can influence treatment.

resultsConsensus members describe how to perform a dynamic assessment to optimize the dose and injection technique for each patient. A tailored treatment protocol is described for men and women with a wide range of forehead presentations. For each presentation, units of toxin as well as the precise location of injection points were defined by creating a 12-zone map of the forehead.

conclusionThese recommendations depart from traditional consensus documents by providing detailed incobotulinumtoxinA injection protocols for the forehead based on the major parameters that differ between patients, including muscular anatomy, size, and tone. It is expected that the use of this document will lead to more satisfactory, natural, and individualized aesthetic outcomes for patients.

Indexed as

Bocoutureforehead linesfrontalisincobotulinumtoxinAXeomin

Identifiers

PMID29089780
PMCPMC5655032

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.