Evidence map›Paper›PMID 29089760›Full record

ArticleInternational journal of nanomedicine2017

Iron oxide magnetic nanoparticles combined with actein suppress non-small-cell lung cancer growth in a p53-dependent manner.

Ming-Shan Wang, Liang Chen, Ya-Qiong Xiong, Jing Xu, Ji-Peng Wang, Zi-Li Meng

Open access · goldAbstract read
In one paragraph

Article in International journal of nanomedicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 32 citations in OpenAlex.

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  8. Nano-TRAIL: a promising path to cancer therapy.Cancer drug resistance (Alhambra, Calif.) · 2023
    Review
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  13. Influence of luminescent graphene quantum dots on trypsin activity.International journal of nanomedicine · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Ming-Shan WangDepartment of Oncology, Huaiyin Hospital of Huai'an City, Huai'an, China.
Liang ChenDepartment of Respiration, Huai'an First People's Hospital, Nanjing Medical University, Huai'an, China.
Ya-Qiong XiongDepartment of Respiration, Huai'an First People's Hospital, Nanjing Medical University, Huai'an, China.
Jing XuDepartment of Respiration, Huai'an First People's Hospital, Nanjing Medical University, Huai'an, China.
Ji-Peng WangDepartment of Respiration, Huai'an First People's Hospital, Nanjing Medical University, Huai'an, China.
Zi-Li MengDepartment of Respiration, Huai'an First People's Hospital, Nanjing Medical University, Huai'an, China.
Huaian First People’s Hospital · CNNanjing Medical University · CNSecond People’s Hospital of Huai’an · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Actein (AT) is a triterpene glycoside isolated from the rhizomes of

Indexed as

AnimalsAntineoplastic Agents, PhytogenicAntineoplastic Combined Chemotherapy ProtocolsApoptosisCarcinoma, Non-Small-Cell LungCaspase 3Cell Line, TumorFerric CompoundsGenes, p53HumansLung NeoplasmsMagnetite NanoparticlesMaleMice, NudeProto-Oncogene Proteins c-bcl-2SaponinsacteinAntineoplastic Agents, PhytogenicCASP3 protein, humanCaspase 3Ferric Compoundsferric oxideMagnetite NanoparticlesProto-Oncogene Proteins c-bcl-2SaponinsTriterpenesacteinapoptosisFe3O4 magnetic nanoparticlesNSCLCp53

Identifiers

PMID29089760
PMCPMC5655152
OpenAlexW2766935814

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.