Evidence map›Paper›PMID 29089696›Full record

ArticleThe Indian journal of surgery2017

The Effects of Simvastatin on Ischemia Reperfusion Injury in an Experimental Colon Anastomosis Model.

Mahmut Akarsu, Oral Saygun, Kuzey Aydinuraz, Oktay Aydin, Cagatay Erden Daphan, Fatma Benli Tanrıkulu, Ucler Kisa, Faruk Metin Comu

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Indian journal of surgery, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.1field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Mahmut AkarsuDepartment of General Surgery, Medical Faculty, Kırıkkale University, Kırıkkale, Turkey.
Oral SaygunDepartment of General Surgery, Medical Faculty, Kırıkkale University, Kırıkkale, Turkey.
Kuzey AydinurazDepartment of General Surgery, Medical Faculty, Kırıkkale University, Kırıkkale, Turkey.
Oktay AydinDepartment of General Surgery, Medical Faculty, Kırıkkale University, Kırıkkale, Turkey.
Cagatay Erden DaphanDepartment of General Surgery, Medical Faculty, Kırıkkale University, Kırıkkale, Turkey.
Fatma Benli TanrıkuluDepartment of Pathology, Medical Faculty, Kırıkkale University, Kırıkkale, Turkey.
Ucler KisaDepartment of Biochemistry, Medical Faculty, Kırıkkale University, Kırıkkale, Turkey.
Faruk Metin ComuDepartment of Physiology, Medical Faculty, Kırıkkale University, Kırıkkale, Turkey.
Kırıkkale University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Anastomotic leakage is more frequently reported in colonic anastomoses. Ischemia reperfusion injury is one of the main reasons for anastomotic leakage. Simvastatin is known to prevent tissue damage induced by free oxygen radicals after ischemia reperfusion injury. The effect of simvastatin on colonic anastomosis impaired by ischemia reperfusion injury is investigated. Single layer, end-to-end colocolic anastomosis after 0.5-cm colon resection was performed in Wistar Albino rats. In Group 1 (control) (

Indexed as

Anastomotic healingColonIschemia reperfusionRatSimvastatinSuperior mesenteric artery occlusion

Identifiers

PMID29089696
PMCPMC5653570
OpenAlexW2346423446

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.