ArticleScientific reports2017
Helicobacter pylori colonization and obesity - a Mendelian randomization study.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
18 citing papers in PubMed, 32 citations in OpenAlex.
- Article
- Serum metabolic profiling analysis of chronic gastritis and gastric cancer by untargeted metabolomics.Annals of medicine and surgery (2012) · 2025Article
- Systematic Review of Mendelian Randomization Studies onInterdisciplinary perspectives on infectious diseases · 2025Review
- Relationship between Helicobacter pylori infection and visceral fat area in diabetic populations: the mediating role of insulin resistance.Frontiers in cellular and infection microbiology · 2025Article
- Bidirectional Mendelian randomization to explore the causal relationships between the gut microbiota and male reproductive diseases.Scientific reports · 2024Article
- Obesity, abdominal obesity, metabolic obesity phenotypes, and Helicobacter pylori infection: results from NHANES 1999-2000.BMC infectious diseases · 2024Article
- Effect ofJournal of neurogastroenterology and motility · 2023Article
- Microbiome Dysbiosis: A Pathological Mechanism at the Intersection of Obesity and Glaucoma.International journal of molecular sciences · 2023Review
- Body mass index is associated withThe Journal of international medical research · 2022Article
- Association betweenFrontiers in endocrinology · 2022Article
- The association between Helicobacter pylori and obesity: a systematic review and meta-analysis of case-control studies.Clinical diabetes and endocrinology · 2021Article
- Gut Microbiota: The Missing Link BetweenFrontiers in endocrinology · 2021Review
- Helicobacter pylori Related Diseases and Osteoporotic Fractures (Narrative Review).Journal of clinical medicine · 2020Review
- Article
- The Influences of Visceral Fat Area on the Sites of Esophageal Mucosal Breaks in Subjects with Gastroesophageal Reflux Diseases.Gastroenterology research and practice · 2019Article
- Article
- First-lineInfection and drug resistance · 2019Article
- Article
Corrections and comments
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Authors and funding
11 authors at 5 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Obesity is associated with substantial morbidity, costs, and decreased life expectancy, and continues to rise worldwide. While etiological understanding is needed for prevention, epidemiological studies indicated that colonization with Helicobacter pylori (H. pylori) may affect body mass index (BMI), but with inconsistent results. Here, we examine the relationship between H. pylori colonization and BMI/obesity. Cross-sectional analyses were performed in two independent population-based cohorts of elderly from the Netherlands and Germany (n = 13,044). Genetic risk scores were conducted based on genetic loci associated with either H. pylori colonization or BMI/obesity. We performed a bi-directional Mendelian randomization. Meta-analysis of cross-sectional data revealed no association between anti-H. pylori IgG titer and BMI, nor of H. pylori positivity and BMI. Anti-H. pylori IgG titer was negatively associated with obesity (OR 0.99972; 95% CI 0.99946-0.99997, p = 0.03) and with obesity classes (Beta -6.91 •10
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