Evidence map›Paper›PMID 29089524›Full record

ArticleScientific reports2017

Characterization of an industry-grade CMOS camera well suited for single molecule localization microscopy - high performance super-resolution at low cost.

Robin Diekmann, Katharina Till, Marcel Müller, Matthias Simonis, Mark Schüttpelz, Thomas Huser

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
7.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 54 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 2 countries.

Robin DiekmannDepartment of Physics, Bielefeld University, Bielefeld, Germany.ORCID 0000-0002-5290-9123
Katharina TillDepartment of Physics, Bielefeld University, Bielefeld, Germany.
Marcel MüllerDepartment of Physics, Bielefeld University, Bielefeld, Germany.
Matthias SimonisDepartment of Physics, Bielefeld University, Bielefeld, Germany.
Mark SchüttpelzDepartment of Physics, Bielefeld University, Bielefeld, Germany.
Thomas HuserDepartment of Physics, Bielefeld University, Bielefeld, Germany. thomas.huser@physik.uni-bielefeld.de.ORCID 0000-0003-2348-7416
Bielefeld University · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Many commercial as well as custom-built fluorescence microscopes use scientific-grade cameras that represent a substantial share of the instrument's cost. This holds particularly true for super-resolution localization microscopy where high demands are placed especially on the detector with respect to sensitivity, noise, and also image acquisition speed. Here, we present and carefully characterize an industry-grade CMOS camera as a cost-efficient alternative to commonly used scientific cameras. Direct experimental comparison of these two detector types shows widely similar performance for imaging by single molecule localization microscopy (SMLM). Furthermore, high image acquisition speeds are demonstrated for the CMOS detector by ultra-fast SMLM imaging.

Identifiers

PMID29089524
PMCPMC5663701
OpenAlexW2766946019

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.