Evidence map›Paper›PMID 29089442›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2017

Extinction of Contextual Cocaine Memories Requires Ca

Caitlin E Burgdorf, Kathryn C Schierberl, Anni S Lee, Delaney K Fischer, Tracey A Van Kempen, Vladimir Mudragel, Richard L Huganir, Teresa A Milner, Michael J Glass, Anjali M Rajadhyaksha

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 34 citations in OpenAlex.

  1. Article
  2. Astrocytic abnormalities in brain-specificChannels (Austin, Tex.) · 2025
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  14. Review
  15. Contribution of D1R-expressing neurons of the dorsal dentate gyrus and CaNeuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2020
    Article
  16. Prior cocaine self-administration impairs attention signals in anterior cingulate cortex.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2020
    Article
  17. Article
  18. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Caitlin E BurgdorfDivision of Pediatric Neurology, Department of Pediatrics, and.ORCID 0000-0001-7261-929X
Kathryn C SchierberlDivision of Pediatric Neurology, Department of Pediatrics, and.ORCID 0000-0003-3881-1776
Anni S LeeDivision of Pediatric Neurology, Department of Pediatrics, and.
Delaney K FischerDivision of Pediatric Neurology, Department of Pediatrics, and.
Tracey A Van KempenFeil Family Brain and Mind Research Institute, Weill Cornell Medicine, New York, New York 10065.
Vladimir MudragelFeil Family Brain and Mind Research Institute, Weill Cornell Medicine, New York, New York 10065.
Richard L HuganirSolomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, and.ORCID 0000-0001-9783-5183
Teresa A MilnerFeil Family Brain and Mind Research Institute, Weill Cornell Medicine, New York, New York 10065.ORCID 0000-0002-0458-6569
Michael J GlassFeil Family Brain and Mind Research Institute, Weill Cornell Medicine, New York, New York 10065.
Anjali M RajadhyakshaDivision of Pediatric Neurology, Department of Pediatrics, and amr2011@med.cornell.edu.
Cornell University · USJohns Hopkins University · USPediatrics and Genetics · US

Funding

UCD Mutant Mouse Regional Resource CenterU42OD012210 · OD · UNIVERSITY OF CALIFORNIA AT DAVIS · PI KC KENT LLOYD · 2012 to 2026
$29.2M
ULTRASTRUCTURAL INTERACTIONS OF OPIOIDS IN HIPPOCAMPUSR01DA008259 · NIDA · WEILL MEDICAL COLL OF CORNELL UNIV · PI MILNER, TERESA A · 1993 to 2019
$6.4M
Contribution of G protein coupled estrogen receptor to changes in hypothalamic plasticity and hypertension susceptibility in mice with accelerated ovarian failureR01HL136520 · NHLBI · WEILL MEDICAL COLL OF CORNELL UNIV · PI MICHAEL J GLASS, Teresa A Milner · 2017 to 2026
$5.0M
PHARMACOLOGY AND NEUROSCIENCE OF DRUG ABUSET32DA007274 · NIDA · WEILL MEDICAL COLL OF CORNELL UNIV · PI SZETO, HAZEL H · 1991 to 2011
$4.8M
The Role of Cav1.2 L-type Ca2+ Channels in Cocaine-Induced ReinstatementR01DA029122 · NIDA · WEILL MEDICAL COLL OF CORNELL UNIV · PI RAJADHYAKSHA, ANJALI M · 2012 to 2016
$2.1M
Hypothalamic cytokines, glutamate receptor plasticity, and blood pressureR01HL135498 · NHLBI · WEILL MEDICAL COLL OF CORNELL UNIV · PI GLASS, MICHAEL J · 2017 to 2020
$1.7M
MENOPAUSAL CHANGES IN HYPOTHALAMUS AND HYPERTENSION SUSCEPTIBILITYR01HL098351 · NHLBI · WEILL MEDICAL COLL OF CORNELL UNIV · PI MILNER, TERESA A · 2011 to 2014
$1.7M
Genetic and Environmental Influences on AddictionT32DA039080 · NIDA · WEILL MEDICAL COLL OF CORNELL UNIV · PI Teresa A Milner · 2017 to 2026
$1.4M
Cav1.2 as a novel target for cocaine addiction pharmacotherapyF31DA032169 · NIDA · WEILL MEDICAL COLL OF CORNELL UNIV · PI LEE, ANNI SEUNGEUN · 2012 to 2015
$147k
NHLBI NIH HHS R01 HL098351NHLBI NIH HHS R01 HL135498NHLBI NIH HHS R01 HL136520NIDA NIH HHS F31 DA032169NIDA NIH HHS R01 DA008259NIDA NIH HHS R01 DA029122NIDA NIH HHS T32 DA007274NIDA NIH HHS T32 DA039080NIH HHS U42 OD012210
6 · The paper itself

Abstract

Exposure to cocaine-associated contextual cues contributes significantly to relapse. Extinction of these contextual associations, which involves a new form of learning, reduces cocaine-seeking behavior; however, the molecular mechanisms underlying this process remain largely unknown. We report that extinction, but not acquisition, of cocaine conditioned place preference (CPP) in male mice increased Ca

Indexed as

AnimalsCalcium Channels, L-TypeCocaineCocaine-Related DisordersExtinction, PsychologicalGene ExpressionHippocampusMaleMemoryMiceMice, Inbred C57BLMice, TransgenicReceptors, Dopamine D1Signal TransductionSingle-Blind MethodCACNA1C protein, mouseCalcium Channels, L-TypeCocaineReceptors, Dopamine D1CaMKIICav1.2cocainedopamine D1 receptorextinctionGluA1

Identifiers

PMID29089442
PMCPMC5719973
OpenAlexW2766370665

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.