Evidence map›Paper›PMID 29089428›Full record

ArticlemBio2017

Associations among Antibiotic and Phage Resistance Phenotypes in Natural and Clinical

Richard C Allen, Katia R Pfrunder-Cardozo, Dominik Meinel, Adrian Egli, Alex R Hall

Abstract read
In one paragraph

Article in mBio, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed.

  1. Review
  2. Phage-Based Approaches to ChronicAntibiotics (Basel, Switzerland) · 2026
    Review
  3. Article
  4. Review
  5. Article
  6. Hard to jump: host shifts appear unlikely in a T4-like phage evolved in the lab.Frontiers in cellular and infection microbiology · 2025
    Article
  7. Review
  8. Article
  9. Article
  10. Review
  11. Review
  12. Review
  13. Article
  14. Review
  15. Phage Therapy in Livestock and Companion Animals.Antibiotics (Basel, Switzerland) · 2021
    Review
  16. Article
  17. Review
  18. Temporal encoding of bacterial identity and traits in growth dynamics.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Richard C AllenInstitute for Integrative Biology, Department of Environmental Systems Science, ETH Zürich, Zürich, Switzerland richard.allen@env.ethz.ch alex.hall@env.ethz.ch.ORCID 0000-0001-6012-7888
Katia R Pfrunder-CardozoInstitute for Integrative Biology, Department of Environmental Systems Science, ETH Zürich, Zürich, Switzerland.
Dominik MeinelDivision of Clinical Microbiology, University Hospital Basel, Basel, Switzerland.
Adrian EgliDivision of Clinical Microbiology, University Hospital Basel, Basel, Switzerland.
Alex R HallInstitute for Integrative Biology, Department of Environmental Systems Science, ETH Zürich, Zürich, Switzerland richard.allen@env.ethz.ch alex.hall@env.ethz.ch.ORCID 0000-0002-3654-1373

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The spread of antibiotic resistance is driving interest in new approaches to control bacterial pathogens. This includes applying multiple antibiotics strategically, using bacteriophages against antibiotic-resistant bacteria, and combining both types of antibacterial agents. All these approaches rely on or are impacted by associations among resistance phenotypes (where bacteria resistant to one antibacterial agent are also relatively susceptible or resistant to others). Experiments with laboratory strains have shown strong associations between some resistance phenotypes, but we lack a quantitative understanding of associations among antibiotic and phage resistance phenotypes in natural and clinical populations. To address this, we measured resistance to various antibiotics and bacteriophages for 94 natural and clinical

Indexed as

AnimalsAnti-Bacterial AgentsColiphagesDrug Resistance, BacterialEscherichia coliEscherichia coli InfectionsEvolution, MolecularGenome, BacterialHumansPhage TherapyPhenotypePlasmidsReceptors, VirusAnti-Bacterial AgentsReceptors, Virusantibiotic resistancebacteriophagesEscherichia colievolutionmicrobial ecologyplasmids

Identifiers

PMID29089428
PMCPMC5666156

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.